Document Detail


Canine urinary bladder epithelial cells: preparation for cell culture by enzyme dispersion.
MedLine Citation:
PMID:  195376     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In a qualitative and quantitative study of enzymic dispersion of cells from the mucosal layer stripped from canine urinary bladder, trypsin was found to be equal or superior to the other enzymes tested for dispersal of urothelial cells specifically. Collagenase or collagenase plus trypsin served to disperse the whole tissue. A procedure for recovering the urothelial cells as a single-cell suspension and establishing them in culture is presented. The morphology, culture behaviour, and chromosome complement of these cells is described.
Authors:
R A Bonar; C F Reich; Y Sharief
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Urological research     Volume:  5     ISSN:  0300-5623     ISO Abbreviation:  Urol. Res.     Publication Date:  1977  
Date Detail:
Created Date:  1977-08-12     Completed Date:  1977-08-12     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0364311     Medline TA:  Urol Res     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  87-94     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Culture Techniques
Dogs
Epithelial Cells
Epithelium / enzymology
Microbial Collagenase / metabolism
Trypsin / metabolism
Urinary Bladder / enzymology*,  pathology
Chemical
Reg. No./Substance:
EC 3.4.21.4/Trypsin; EC 3.4.24.3/Microbial Collagenase

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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