Document Detail


Canine status epilepticus due to acute intoxication.
MedLine Citation:
PMID:  22215313     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Objectives: The purpose of this study was to describe the type of toxin ingested, clinical presentation and outcome of dogs with status epilepticus (SE) due to acute poisoning presented to a large referral veterinary hospital. Materials and methods: Retrospective case series. Medical records of all dogs suffering from SE were reviewed (Jan 1, 2002 to April 30, 2009). Results: Fourteen dogs with SE due to acute intoxication were identified. Toxicological analyses (qualitative analysis with gas chromatography/mass spectrometry; n=11) detected poisonings with carbofuran, crimidine, paraoxone, metaldehyde, strychnine and diazinon. In the other three cases the uptake of a known poison was observed (zink phosphide, metaldehyde). None of the dogs showed evidence of neurological disease up to the day of presentation. The dogs were hospitalised for 2-10 days (median 5 days). The survival rate was 85.7%. None of the dogs experienced any more seizures after discharge (median observation period 2.6 years). Conclusion and clinical relevance: Ancillary to the acute clinical presentation, preliminary reports (possible uptake of poisonous material) and an inconspicuous medical history may suggest a tentative diagnosis. Managed adequately, these patients can have a high survival rate. Clinicians should also keep uncommon intoxications in mind.
Authors:
R Zimmermann; T A Steinberg; K Raith; V Hülsmeyer; A Fischer
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere     Volume:  38     ISSN:  1434-1239     ISO Abbreviation:  Tierarztl Prax Ausg K Kleintiere Heimtiere     Publication Date:  2010  
Date Detail:
Created Date:  2012-01-04     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9717383     Medline TA:  Tierarztl Prax Ausg K Kleintiere Heimtiere     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  285-94     Citation Subset:  -    
Affiliation:
PD Dr. Andrea Fischer, Medizinische Kleintierklinik, Abteilung für Neurologie, Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München, E-Mail: andrea.fischer@med.vetmed.uni-muenchen.de.
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