Document Detail

Canine herpesvirus during pregnancy and non-pregnant luteal phase.
MedLine Citation:
PMID:  23279539     Owner:  NLM     Status:  In-Data-Review    
Canine herpesvirus (CHV) is a widespread infection among dogs that typically get latently infected after exposure and can reactivate the infection after stress. The aim of the present study was to study the effects of latent CHV infection during pregnancy on pregnancy outcome, and to study if there are signs of genital viral reactivation during pregnancy or during non-pregnant luteal phase. Twelve mated bitches and eight control bitches were followed and sampled regularly during pregnancy or non-pregnant luteal phase. Blood samples were taken for antibody analysis and vaginal swabs for real-time PCR analysis. Three of the pregnant bitches were vaccinated against CHV during pregnancy. All bitches had antibodies to CHV. Two pregnant bitches that were not vaccinated had a twofold or larger increase in CHV titre, with no negative effects detected on pregnancy. Higher titres were not associated with smaller litters or with vaccination. There was no consistent variation in antibody titres due to pregnancy or non-pregnant luteal phase. Vaginal excretion of CHV was not detected from any of the bitches.
B Ström Holst; M Hagberg Gustavsson; M Grapperon-Mathis; I Lilliehöök; A Johannisson; M Isaksson; A Lindhe; E Axnér
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Reproduction in domestic animals = Zuchthygiene     Volume:  47 Suppl 6     ISSN:  1439-0531     ISO Abbreviation:  Reprod. Domest. Anim.     Publication Date:  2012 Dec 
Date Detail:
Created Date:  2013-01-02     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9015668     Medline TA:  Reprod Domest Anim     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  362-5     Citation Subset:  IM    
Copyright Information:
© 2012 Blackwell Verlag GmbH.
Department of Clinical Sciences, Swedish University of Agricultural Sciences, Uppsala, Sweden; National Veterinary Institute, Uppsala, Sweden; Centre for Reproductive Biology in Uppsala (CRU), Uppsala, Sweden.
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