| Canine nephrotoxicosis induced by melamine-contaminated pet food in Italy. | |
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MedLine Citation:
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PMID: 19915330 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Two young dogs belonging to the same kennel placed nearby Treviso (north-eastern Italy) died at the end of 2008 with clinical signs of renal failure. They were subjected to necropsy and were evaluated for histopathological and toxicological changes. Both the animals had same clinical signs and laboratory evidence of uremia. Post mortem investigations revealed severe nephrotoxicosis, associated with uroliths deposition within renal tubules and pelvis. The predominant crystal type was identical to those observed in the kidneys of animals involved in the 2004 and 2007 melamine-associated renal failure epidemic in Asia and US, providing evidence that they share the same causative agent. High doses of melamine were detected in the pet food administered to the dogs, likewise melamine was identified in renal tissue from one dead dog and in urine samples from both the animals. Therefore, a diagnosis of melamine-related nephrotoxicosis was made. To the author's knowledge this is the first report about melamine contamination of pet food from EU. |
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Authors:
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Monia Cocchi; Marta Vascellari; Albino Gallina; Fabrizio Agnoletti; Roberto Angeletti; Franco Mutinelli |
Publication Detail:
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Type: Journal Article Date: 2009-11-13 |
Journal Detail:
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Title: The Journal of veterinary medical science / the Japanese Society of Veterinary Science Volume: 72 ISSN: 0916-7250 ISO Abbreviation: J. Vet. Med. Sci. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2010-02-05 Completed Date: 2010-05-04 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105360 Medline TA: J Vet Med Sci Country: Japan |
Other Details:
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Languages: eng Pagination: 103-7 Citation Subset: IM |
Affiliation:
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Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Universit?, Legnaro, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animal Feed
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analysis* Animals Disease Outbreaks / veterinary Dog Diseases / chemically induced*, epidemiology, pathology Dogs Food Contamination Italy / epidemiology Kidney / pathology Kidney Diseases / chemically induced, pathology, veterinary* Triazines / toxicity* |
| Chemical | |
Reg. No./Substance:
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0/Triazines; 108-78-1/melamine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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