Document Detail

Candidate gene expression and intramuscular fat content in pigs.
MedLine Citation:
PMID:  21214641     Owner:  NLM     Status:  In-Process    
Seventy-two pigs of three genetic groups (Brazilian indigenous breed Piau, Commercial line and Crossbred) of both sexes were slaughtered at four live weights (30, 60, 90 and 120 kg). Intramuscular fat (IMF) content in Longissimus dorsi muscle of each animal was extracted and correlated with candidate gene mRNA expression (ATN1, EEF1A2, FABP3, LDLR, MGP, OBSCN, PDHB, TRDN and RYR1). Within slaughter weight of 120 kg, Piau and Crossbred pigs showed higher IMF content (p < 0.05) than commercial animals, with 2.48, 2.08 and 1.00% respectively. Barrows presented higher values of IMF (p < 0.05) than gilts (1.54 and 1.30% respectively). Gene expression of EEF1A2, FABP3, LDLR, OBSCN, PDHB, TRDN and RYR1 were correlated with IMF (p < 0.05) using the whole dataset. For Piau data only, expression of FABP3, LDLR, MGP, OBSCN, PDHB, TRDN and RYR1 showed correlation with IMF (p < 0.05). Genes that have important roles in lipid transportation inside the cell (FABP3) and tissues (LDLR) showed correlation with IMF of, respectively, 0.68 and 0.63 using the whole data set, and 0.90 and 0.91 using data from Piau animals. The highly positive correlation of the LDLR and FAPB3 expression with IMF content may confirm that these genes are important for fat deposition in the porcine L. dorsi muscle.
N V L Serão; R Veroneze; A M F Ribeiro; L L Verardo; J Braccini Neto; E Gasparino; C F Campos; P S Lopes; S E F Guimarães
Publication Detail:
Type:  Journal Article     Date:  2010-10-28
Journal Detail:
Title:  Journal of animal breeding and genetics = Zeitschrift für Tierzüchtung und Züchtungsbiologie     Volume:  128     ISSN:  1439-0388     ISO Abbreviation:  J. Anim. Breed. Genet.     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-01-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100955807     Medline TA:  J Anim Breed Genet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  28-34     Citation Subset:  IM    
Copyright Information:
© 2010 Blackwell Verlag GmbH.
Departamento de Zootecnia, Universidade Federal de Viçosa, Viçosa, Brazil.
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