Document Detail

Candida strains from neonates in a special care baby unit.
MedLine Citation:
PMID:  1536586     Owner:  NLM     Status:  MEDLINE    
Carriage and acquisition of Candida spp and Candida albicans biotypes were studied among 163 neonates and 90 staff in a neonatal intensive care and surgical unit during a 17 week period. Twenty one neonates carried yeasts in the mouth, rectum or groin when first sampled, and a further 25 were positive later. C albicans accounted for 94.7% of 431 yeast isolates from neonates but only 67.4% of 43 isolates from staff. The first isolated C albicans biotype persisted in 13 babies monitored longitudinally. Simultaneous colonisation with two Candida spp was found in 2/46 neonates and 5/33 staff. The prevalence of candida was significantly higher among babies of gestational age less than 28 weeks (65%) than those of higher gestational age (26%). Oral and/or crural candida infection was observed in 14 of the babies but none developed deep seated candidosis. Routine antifungal prophylaxis did not affect the frequency of yeasts among the neonates.
A M Sharp; F C Odds; E G Evans
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  67     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  1992 Jan 
Date Detail:
Created Date:  1992-03-23     Completed Date:  1992-03-23     Revised Date:  2010-09-07    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  48-52     Citation Subset:  AIM; IM    
Department of Microbiology, University of Leeds.
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MeSH Terms
Candida / isolation & purification*
Candida albicans / isolation & purification
Gestational Age
Infant, Newborn / microbiology*
Infant, Premature / microbiology
Intensive Care Units, Neonatal
Longitudinal Studies
Medical Staff, Hospital
Mouth / microbiology*
Mycology / methods
Rectum / microbiology*
Skin / microbiology*
Grant Support
//Wellcome Trust

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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