Document Detail


Candida spp. prevalence in well controlled type 2 diabetic patients with denture stomatitis.
MedLine Citation:
PMID:  21569989     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: The aim of this study was to compare the prevalence of Candida spp. in diabetics and nondiabetics with and without denture stomatitis (DS).
STUDY DESIGN: Mycologic samples were taken from the dentures of 90 healthy subjects (control group [CG]), 80 denture stomatitis nondiabetics (DSND), and 40 denture stomatitis diabetics (DSD; well controlled type 2) for identification of Candida spp. Results were analyzed by Fisher exact test, Bonferroni-corrected confidence interval, and χ(2) test (α = .05).
RESULTS: Candida albicans was the predominant species isolated (81.9%; P < .016), with C. tropicalis and C. glabrata demonstrating similar prevalence (15.71% and 15.24%, respectively). The prevalence of C. albicans and C. tropicalis in the DS groups were significantly higher (P < .01) than in the CG. The prevalence of C. tropicalis significantly increased with the highest degree of inflammation (P < .05).
CONCLUSIONS: The prevalence of Candida spp. was similar between diabetic and nondiabetic patients with DS. Candida tropicalis may play a role in the progression of DS.
Authors:
Paula Volpato Sanitá; Ana Cláudia Pavarina; Eunice Teresinha Giampaolo; Mariana Montenegro Silva; Ewerton Garcia de Oliveira Mima; Daniela Garcia Ribeiro; Carlos Eduardo Vergani
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics     Volume:  111     ISSN:  1528-395X     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Publication Date:  2011 Jun 
Date Detail:
Created Date:  2011-05-16     Completed Date:  2011-10-14     Revised Date:  2012-01-04    
Medline Journal Info:
Nlm Unique ID:  9508562     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol Endod     Country:  United States    
Other Details:
Languages:  eng     Pagination:  726-33     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2011 Mosby, Inc. All rights reserved.
Affiliation:
Araraquara Dental School, UNESP - Univ Estadual Paulista, Araraquara, São Paulo, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Aged
Blood Glucose / metabolism
Candida / classification,  isolation & purification*
Case-Control Studies
Chi-Square Distribution
Cross-Sectional Studies
Dental Prosthesis / adverse effects,  microbiology*
Dentures / adverse effects*
Diabetes Mellitus, Type 2 / blood,  complications,  microbiology*
Female
Humans
Male
Middle Aged
Mouth / microbiology
Reference Values
Sex Factors
Statistics, Nonparametric
Stomatitis, Denture / blood,  complications,  microbiology*
Chemical
Reg. No./Substance:
0/Blood Glucose

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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