| Candida parapsilosis endocarditis: a comparative review of the literature. | |
| | |
MedLine Citation:
|
PMID: 17805589 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Fungal endocarditis (FE) is an uncommon disease, and while accounting for only 1.3-6% of all cases of infectious endocarditis, it carries a high mortality risk. Although Candida albicans represents the main etiology of FE, C. parapsilosis is the most common non-albicans species. We report the case of a 32-year-old man with a history of prior intravenous drug (IVD) use hospitalized with endocarditis due to C. parapsilosis and review all 71 additional cases documented in the literature. A retrospective analysis of the 72 C. parapsilosis cases compared to 52 recently reviewed cases of C. albicans endocarditis was conducted to identify organism-specific clinical peculiarities. The most common predisposing factor for C. parapsilosis endocarditis (41/72; 57.4%) involved prosthetic valves followed by IVD use (12/72; 20%). Peripheral embolic and/or hemorrhagic events occurred in 28/64 (43.8%) patients, mostly in cerebral and lower limb territories. Overall mortality was 41.7%. Combined surgical and clinical treatment was associated with a lower mortality. Few patients received the newer antifungal agents, and it would appear that more experience is required for their use in the treatment of C. parapsilosis endocarditis. |
| | |
Authors:
|
C Garzoni; V A Nobre; J Garbino |
Related Documents
:
|
20495509 - Nontoxinogenic corynebacterium diphtheriae as a rare cause of native endocarditis in ch... 11147029 - Aspergillus endocarditis in a lung transplant recipient. a case report and review of th... 20684779 - Tropheryma whipplei tricuspid endocarditis: a case report and review of the literature. 2599549 - Tricuspid valve replacement for gross tricuspid insufficiency due to dysplastic valve--... 3759799 - Pathological anatomy of ventricular septal defect associated with aortic valve prolapse... 8834719 - Management of mitral valve stenosis in pregnancy: case presentation and review of the l... 7446389 - Right ventricular endomyocardial fibrosis simulating ebstein's anomaly. 23285459 - A malignant transformation in a pre-existing benign scrotal naevus. 6700909 - Cesarean delivery for fetal distress without maternal consent. |
Publication Detail:
|
Type: Case Reports; Journal Article; Review |
Journal Detail:
|
Title: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology Volume: 26 ISSN: 0934-9723 ISO Abbreviation: Eur. J. Clin. Microbiol. Infect. Dis. Publication Date: 2007 Dec |
Date Detail:
|
Created Date: 2007-11-08 Completed Date: 2007-12-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8804297 Medline TA: Eur J Clin Microbiol Infect Dis Country: Germany |
Other Details:
|
Languages: eng Pagination: 915-26 Citation Subset: IM |
Affiliation:
|
Division of Infectious Diseases, University Hospitals of Geneva, 24 Rue Micheli-du-Crest, Geneva 14, Switzerland. Christian.Garzoni@insel.ch |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Antifungal Agents / therapeutic use Candida* / classification Candidiasis / diagnosis, drug therapy, microbiology* Endocarditis / drug therapy, microbiology* Humans Male |
| Chemical | |
Reg. No./Substance:
|
0/Antifungal Agents |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Evidence of shared risk for Alzheimer's disease and Parkinson's disease using family history.
Next Document: Chemical composition of the wax secreted by a scale insect (Ceroplastes pseudoceriferus Green).