| Candida meningoencephalitis treated with 5-fluorocytosine. | |
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MedLine Citation:
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PMID: 841284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The successful treatment of Candida albicans meningoencephalitis with 5-fluorocytosine (5-FC) is reported. After abdominal surgery with many complications, a 60-year-old man developed severe headache, lumbar pain, mental change. The significance of this was not realized for months. The cerebrospinal fluid (CSF) showed pleocytosis, high protein and low glucose concentration. One CSF culture out of 6 revealed growth of Candida albicans. Serologic tests are also indicated candida infection. After a month of treatment with 5-FC, the severe pain decreased and he improved mentally. After 4 months, the CSF was normal and the 5-FC treatment ended. For the past year, the patient has not shown any signs of relapse. |
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Authors:
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L Nordström; S Oistämö; F Olmebring |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Scandinavian journal of infectious diseases Volume: 9 ISSN: 0036-5548 ISO Abbreviation: Scand. J. Infect. Dis. Publication Date: 1977 |
Date Detail:
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Created Date: 1977-04-15 Completed Date: 1977-04-15 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0215333 Medline TA: Scand J Infect Dis Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 63-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Candidiasis
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drug therapy* Cytosine / analogs & derivatives* Flucytosine / therapeutic use* Humans Male Meningoencephalitis / drug therapy* Middle Aged |
| Chemical | |
Reg. No./Substance:
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2022-85-7/Flucytosine; 71-30-7/Cytosine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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