Document Detail

Candida laryngotracheitis: a complication of combined steroid and antibiotic usage in croup.
MedLine Citation:
PMID:  1563933     Owner:  NLM     Status:  MEDLINE    
The use of corticosteroids to reduce the morbidity associated with laryngotracheobronchitis (croup) has been a controversial issue for many years. Recent literature, however, does support a decreased morbidity and increased clinical response when short-term steroids are used. As a prophylactic measure against bacterial superinfection, antibiotics are commonly utilized in the treatment of croup. We present the case of an otherwise healthy infant with severe croup who was hospitalized and treated with both steroids and antibiotics. A relapse in her symptoms led to the diagnosis of candida laryngotracheitis. We recommend close monitoring of patients with croup treated aggressively with steroids and antibiotics. Steroid use should be limited to 24 h with antibiotics reserved for patients with signs of bacterial infection.
D M Burton; A B Seid; D B Kearns; S M Pransky
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  International journal of pediatric otorhinolaryngology     Volume:  23     ISSN:  0165-5876     ISO Abbreviation:  Int. J. Pediatr. Otorhinolaryngol.     Publication Date:  1992 Mar 
Date Detail:
Created Date:  1992-05-15     Completed Date:  1992-05-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8003603     Medline TA:  Int J Pediatr Otorhinolaryngol     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  171-5     Citation Subset:  IM    
Children's Hospital and Health Center, San Diego, CA.
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MeSH Terms
Amphotericin B / therapeutic use
Candidiasis / drug therapy,  etiology*
Candidiasis, Oral / drug therapy,  etiology
Cefaclor / adverse effects
Cefuroxime / adverse effects*
Croup / drug therapy*
Dexamethasone / adverse effects*
Ketoconazole / therapeutic use
Laryngitis / drug therapy,  microbiology*
Tracheitis / drug therapy,  microbiology*
Reg. No./Substance:
1397-89-3/Amphotericin B; 50-02-2/Dexamethasone; 53994-73-3/Cefaclor; 55268-75-2/Cefuroxime; 65277-42-1/Ketoconazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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