| Candida glabrata complicating in vitro pregnancy: successful management of subsequent pregnancy. | |
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MedLine Citation:
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PMID: 20840882 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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OBJECTIVE: To report the occurrence of Candida glabrata chorioamnionitis complicating an in vitro fertilization (IVF) pregnancy. DESIGN: Case report. SETTING: University hospital. PATIENT(S): A 30-year-old woman, primagravida, with an IVF dichorionic-diamniotic pregnancy who presented at 15 weeks with vaginal bleeding. INTERVENTION(S): Before embryo transfer in next IVF cycle, vaginal culture from the patient revealed colonization with C. glabrata, which was treated with boric acid. MAIN OUTCOME MEASURE(S): Subsequent pregnancy after eradication of fungal organisms. RESULT(S): The patient's first pregnancy was treated with indomethacin and broad-spectrum antibiotics, but her membranes ruptured, and she delivered both twins at 16 weeks; the autopsy and pathology reports were consistent with C. glabrata chorioamnionitis. After boric acid treatment eradicated the organisms, two embryos were transferred in subsequent IVF treatment; the second pregnancy was uncomplicated, with dichorionic-diamniotic twins, delivered by cesarean section at 38 weeks. CONCLUSION(S): Eradication of vaginal colonization with C. glabrata may prevent infection of the next IVF pregnancy. |
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Authors:
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Obehi A Asemota; Paul Nyirjesy; Rachel Fox; Jack D Sobel |
Publication Detail:
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Type: Journal Article Date: 2010-09-16 |
Journal Detail:
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Title: Fertility and sterility Volume: 95 ISSN: 1556-5653 ISO Abbreviation: Fertil. Steril. Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-24 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: United States |
Other Details:
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Languages: eng Pagination: 803.e1-2 Citation Subset: IM |
Copyright Information:
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Published by Elsevier Inc. |
Affiliation:
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Department of Obstetrics and Gynecology, Drexel University College of Medicine, Philadelphia, Pennsylvania. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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