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Candida esophagitis in an immunocompetent pregnant woman.
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MedLine Citation:
PMID:  18475336     Owner:  NLM     Status:  In-Data-Review    
Background: Nausea and vomiting are common during the first half of pregnancy and usually require only supportive measures. When symptoms are progressive and weight loss occurs, treatable causes should be sought by means of upper gastrointestinal endoscopy. We report a case of an immunocompetent gravida with invasive Candida albicans esophagitis.Case: The immunocompetent primigravida developed progressive nausea, vomiting, epigastric pain, and a 4.1 kg weight loss during the second trimester of pregnancy. Treatment with metoclopramide and cimetidine for presumed gastroesophageal reflux was not effective. The patient had normal T-cell CD4 and CD8 subsets and was human immunodeficiency virus (HIV) antibody negative. Upper gastrointestinal endoscopy revealed C. albicans esophagitis which was treated with oral nystatin. The esophagitis had resolved completely when reassessed postpartum. The use of histamine(2) blockers is associated with an increased risk for fungal esophagitis and may have been a contributing cause in this case.Conclusion: Pregnant patients with persistent nausea, vomiting, and weight loss should be evaluated by endoscopy for fungal esophagitis.
J S Greenspoon; S Kivnick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Infectious diseases in obstetrics and gynecology     Volume:  1     ISSN:  1064-7449     ISO Abbreviation:  Infect Dis Obstet Gynecol     Publication Date:  1993  
Date Detail:
Created Date:  2008-05-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9318481     Medline TA:  Infect Dis Obstet Gynecol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  149-52     Citation Subset:  -    
Division of Maternal-Fetal Medicine Department of Obstetrics-Gynecology Cedars-Sinai Medical Center Los Angeles CA USA.
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Journal Information
Journal ID (nlm-ta): Infect Dis Obstet Gynecol
ISSN: 1064-7449
ISSN: 1098-0997
Publisher: Hindawi Publishing Corporation
Article Information
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Copyright ? 1993 Hindawi Publishing Corporation.
open-access: This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Received Day: 8 Month: 6 Year: 1993
Accepted Day: 19 Month: 10 Year: 1993
Print publication date: Year: 1993
Volume: 1 Issue: 3
First Page: 149 Last Page: 152
ID: 2364304
PubMed Id: 18475336
Publisher Item Identifier: S106474499300033X
DOI: 10.1155/S106474499300033X

Candida Esophagitis in an Immunocompetent Pregnant Woman
Jeffrey S. Greenspoon13
Seth Kivnick2
1Division of Maternal-Fetal MedicineDepartment of Obstetrics-GynecologyCedars-Sinai Medical CenterLos AngelesCAUSA
2Department of Obstetrics-GynecologyKdiser Foundation Hospital-West Los AngelesLos AngelesCAUSA
3Room 1738OB/GYNCedars-Sinai Medical Center8700 Beverly BoulevardLos AngelesCA90048USA

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  • Research Article

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