Document Detail

Candida endocarditis in a premature infant.
MedLine Citation:
PMID:  11125932     Owner:  NLM     Status:  MEDLINE    
Endocarditis is an uncommon complication of invasive candidiasis. We present a fatal case of endocarditis caused by Candida albicans in a very low birth weight infant. The 780-g male infant did not have any structural heart disease and a central venous catheter was not placed. Endocarditis developed in spite of parenteral fluconazole treatment. Echocardiography was a valuable tool in making the diagnosis. The infant died on the 40th day of life. The development of Candida endocarditis in a premature infant who was treated with fluconazole had not been previously reported. In the case of systemic candidiasis, premature infants require very careful monitoring for the progression of the disease, even if antifungal therapy is administered.
G Mogyorósy; G Soós; A Nagy
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of perinatal medicine     Volume:  28     ISSN:  0300-5577     ISO Abbreviation:  J Perinat Med     Publication Date:  2000  
Date Detail:
Created Date:  2000-12-27     Completed Date:  2001-02-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0361031     Medline TA:  J Perinat Med     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  407-11     Citation Subset:  IM    
Department of Pediatrics, University of Debrecen, Debrecen, Hungary.
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MeSH Terms
Candida albicans / isolation & purification
Candidiasis* / drug therapy
Endocarditis / microbiology*,  pathology,  ultrasonography
Fatal Outcome
Fluconazole / therapeutic use
Infant, Newborn
Infant, Premature*
Infant, Very Low Birth Weight*
Lung / microbiology,  pathology
Reg. No./Substance:

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