| Candida albicans morphogenesis and host defence: discriminating invasion from colonization. | |
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MedLine Citation:
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PMID: 22158429 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Candida albicans is a common fungal pathogen of humans that colonizes the skin and mucosal surfaces of most healthy individuals. Until recently, little was known about the mechanisms by which mucosal antifungal defences tolerate colonizing C. albicans but react strongly when hyphae of the same microorganism attempt to invade tissue. In this Review, we describe the properties of yeast cells and hyphae that are relevant to their interaction with the host, and the immunological mechanisms that differentially recognize colonizing versus invading C. albicans. |
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Authors:
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Neil A R Gow; Frank L van de Veerdonk; Alistair J P Brown; Mihai G Netea |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-12-12 |
Journal Detail:
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Title: Nature reviews. Microbiology Volume: - ISSN: 1740-1534 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
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Created Date: 2011-12-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101190261 Medline TA: Nat Rev Microbiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Aberdeen Fungal Group, School of Medical Sciences, Institute of Medical Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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