Document Detail

Candida albicans meningitis and brain abscesses in a neonate: a case report.
MedLine Citation:
PMID:  20853574     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Invasive Candida infection is an increasingly important cause of morbidity and mortality in the neonatal intensive care unit. Neonatal candidemia occurs in 4-15% of extremely low birth weight infants. Meningitis occurs in 5-9% of patients with candidemia. A few infants with Candida meningitis (4%) present ventriculitis or brain abscess.
OBSERVATIONS: We report a neonate born at 34 weeks gestational age, who at 12 days old presented apnea and seizures. Cerebrospinal fluid (CSF) grew Candida Albicans, and blood cultures were negative. A head sonogram and head computed tomography scan were negative. Brain magnetic resonance imaging (MRI) detected multiple brain parenchyma micro abscesses.
CONCLUSIONS: This case confirms the need of obtaining adequate cultures including blood, urine, and CSF when sepsis is suspected. Neuroimaging studies should be included in diagnostic workup of patients with systemic fungal infection. Improved neuroimaging techniques such as MRI may lead to earlier diagnosis of cerebral abscesses.
Ingrid M Ancalle; Juan A Rivera; Inés García; Lourdes García; Marta Valcárcel
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Boletín de la Asociación Médica de Puerto Rico     Volume:  102     ISSN:  0004-4849     ISO Abbreviation:  Bol Asoc Med P R     Publication Date:    2010 Jan-Mar
Date Detail:
Created Date:  2010-09-21     Completed Date:  2010-11-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7505267     Medline TA:  Bol Asoc Med P R     Country:  Puerto Rico    
Other Details:
Languages:  eng     Pagination:  45-8     Citation Subset:  IM    
From the University of Puerto Rico School of Medicine, Department of Pediatrics, Neonatology Section, San Juan, Puerto Rico.
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MeSH Terms
Brain Abscess / microbiology*
Candidiasis / complications*
Infant, Newborn
Meningitis, Fungal / microbiology*

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