| Candesartan in the treatment of hypertension: what have we learnt in the last decade? | |
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MedLine Citation:
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PMID: 21848481 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Introduction: Although all of the first-line antihypertensive drugs effectively reduce blood pressure, there are some conditions that may favor the use of angiotensin receptor blockers over others, such as left ventricular hypertrophy, microalbuminuria, renal dysfunction, diabetes, or metabolic syndrome, among others. Areas covered: This manuscript reviewed the data supporting the use of candesartan cilexetil in hypertensive population with a special focus on its efficacy and safety. For this purpose, a search on MEDLINE and EMBASE databases was performed. The MEDLINE and EMBASE search included both medical subject headings (MeSH) and keywords including: candesartan OR angiotensin receptor blockers OR renin angiotensin system AND hypertension treatment. References of the retrieved articles were also screened for additional studies. There were no language restrictions. Expert opinion: Candesartan, a long-acting angiotensin receptor antagonist, has been shown to be an effective and well-tolerated therapy in the entire spectrum of hypertensive patients, including those at higher risk, such as those with diabetes, metabolic syndrome, left ventricular hypertrophy, or microalbuminuria. |
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Authors:
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Vivencio Barrios; Carlos Escobar |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-17 |
Journal Detail:
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Title: Expert opinion on drug safety Volume: - ISSN: 1744-764X ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-8-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101163027 Medline TA: Expert Opin Drug Saf Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Hospital Ramon y Cajal , Department of Cardiology , Carretera Colmenar Viejo, km 9,100, 28034 Madrid , Spain +34 91 3368259 ; +34 91 3368665 ; vbarriosa@meditex.es. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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