Document Detail

Cancer mortality among populations residing in counties near the Hanford site, 1950-2000.
MedLine Citation:
PMID:  16607175     Owner:  NLM     Status:  MEDLINE    
A descriptive epidemiologic study of cancer mortality among residents of counties near the Hanford nuclear facility site in Richland, Washington, was conducted. Between 1944 and 1957, radioactive 131I was released into the environment from the Hanford site. Cancer mortality from 1950 through 2000 was evaluated in four counties with the highest estimated exposure to 131I and compared with the cancer mortality experience in five demographically similar counties in Washington State with minimal 131I exposure. Overall, cancer rates in the study counties were slightly below those in the comparison counties [relative risk (RR) 0.95; 95% confidence interval (CI) 0.93-0.97], due mainly to a low risk for lung cancer (RR 0.89; 95% CI 0.85-0.93). Thyroid cancer (n=33; RR 0.84; 95% CI 0.56-1.26), female breast cancer (n=1,233; RR 0.99; 95% CI 0.92-1.06), leukemia other than chronic lymphocytic leukemia (n=492; RR 0.95; 95% CI 0.85-1.06), and childhood leukemia (n=71; RR=1.06; 95% CI 0.78-1.43) were not significantly increased in the exposed counties. Furthermore, there was no evidence that the cancer death rates over time differed between study and comparison counties. Patterns over time of thyroid cancer in particular were similar for exposure and comparison counties. Although based on a geographic correlation design, these data suggest that living near the Hanford site has not increased cancer rates.
John D Boice; Michael T Mumma; William J Blot
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Health physics     Volume:  90     ISSN:  0017-9078     ISO Abbreviation:  Health Phys     Publication Date:  2006 May 
Date Detail:
Created Date:  2006-04-11     Completed Date:  2006-05-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2985093R     Medline TA:  Health Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  431-45     Citation Subset:  IM    
International Epidemiology Institute, 1455 Research Blvd., Suite 550, Rockville, MD 20850, and Vanderbilt University Medical School and Vanderbilt-Ingram Cancer Center, Nashville, TN 37232, USA.
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MeSH Terms
Aged, 80 and over
Environmental Exposure / analysis,  statistics & numerical data*
Iodine Radioisotopes / analysis*
Middle Aged
Neoplasms, Radiation-Induced / mortality*
Nuclear Warfare*
Radiation Dosage
Radiation Monitoring / methods,  statistics & numerical data*
Risk Assessment / methods*
Risk Factors
Washington / epidemiology
Reg. No./Substance:
0/Iodine Radioisotopes

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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