| Cancer incidence rate and mortality rate in sickle cell disease patients at Howard University Hospital: 1986-1995. | |
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MedLine Citation:
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PMID: 9257878 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The incidence of cancer in patients with sickle cell disease (SCD) is not known. The 10-year follow-up data on 696 patients with SCD was analyzed at our institution in order to determine the cancer incidence and cancer mortality rates. The age range was 18 to 79 years, with a mean age of 28.8 years. There were 377 females and 319 males. The median follow-up was 3 years. Five patients developed cancer during this period. The cancer incidence rate was 5/2,864 or 1.74 per 1,000 patient years. The 95% CI was 0.64 to 4.32 per 1,000 patient years. There were 68 deaths with 3 being due to cancer. The cancer mortality rate was 3/2,873 or 1.04 cases per 1,000 patient years. Our data represent the first published paper that the authors are aware of, where the cancer incidence and mortality rates have been calculated for any group of patients with SCD. |
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Authors:
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F W Dawkins; K S Kim; R S Squires; R Chisholm; J A Kark; E Perlin; O Castro |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: American journal of hematology Volume: 55 ISSN: 0361-8609 ISO Abbreviation: Am. J. Hematol. Publication Date: 1997 Aug |
Date Detail:
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Created Date: 1997-09-03 Completed Date: 1997-09-03 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7610369 Medline TA: Am J Hematol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 188-92 Citation Subset: IM |
Affiliation:
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Department of Medicine, Howard University College of Medicine, Washington, DC 20060, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Anemia, Sickle Cell / complications*, mortality* District of Columbia / epidemiology Female Follow-Up Studies Humans Incidence Male Middle Aged Neoplasms / epidemiology, etiology* |
| Grant Support | |
ID/Acronym/Agency:
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T25C19376//PHS HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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