Document Detail

Cancer incidence and pattern of arsenic concentration in drinking water wells in Córdoba, Argentina.
MedLine Citation:
PMID:  22017596     Owner:  NLM     Status:  MEDLINE    
Cancer occurrence is associated with Arsenic (As) in drinking water. In Argentina, there are high As concentrations in groundwater but there is no published evidence yet of an association between geographic patterns of cancer incidence and the distribution of As in groundwater supplies. The purpose of this study is to assess the association between cancer incidence patterns and As in Córdoba province's aquifers. Age standardized incidence rates (ASIRs) were obtained from Córdoba Cancer Registry (CCR), and As data from official reports of monitoring wells. A multilevel model was applied. Total ASIRs by aquifers for males/females were 191.01/249.22 (Rioja plain); 215.03/225.37 (Pampa hills); and 239.42/188.93 (Chaco-Pampa plain). As was associated with increased risk of colon cancer in women, and lung and bladder cancers in both sexes. It had no association with breast cancer. ASIRs were related to As, controlling for unobserved heterogeneity. An overlapping pattern of higher As and higher risks was evident for lung, bladder and female colon cancers.
Laura Rosana Aballay; María del Pilar Díaz; Franco Matías Francisca; Sonia Edith Muñoz
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Publication Detail:
Type:  Journal Article     Date:  2011-10-24
Journal Detail:
Title:  International journal of environmental health research     Volume:  22     ISSN:  1369-1619     ISO Abbreviation:  Int J Environ Health Res     Publication Date:  2012  
Date Detail:
Created Date:  2012-05-28     Completed Date:  2012-10-09     Revised Date:  2012-10-31    
Medline Journal Info:
Nlm Unique ID:  9106628     Medline TA:  Int J Environ Health Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  220-31     Citation Subset:  IM    
School of Nutrition, Facultad de Ciencias Médicas, Universidad Nacional de Córdoba, Enrique Barros esq. Enfermera Gordillo, Ciudad Universitaria, Córdoba, 5000, Argentina.
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MeSH Terms
Aged, 80 and over
Argentina / epidemiology
Arsenic* / analysis,  toxicity
Child, Preschool
Drinking Water / analysis*,  standards
Environmental Monitoring* / statistics & numerical data
Infant, Newborn
Middle Aged
Neoplasms / epidemiology*,  etiology
Sex Factors
Water Pollutants, Chemical* / analysis,  toxicity
Water Wells / analysis*,  standards
Young Adult
Reg. No./Substance:
0/Drinking Water; 0/Water Pollutants, Chemical; 7440-38-2/Arsenic

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