| The Canadian off-pump coronary artery bypass graft registry: a one-year prospective comparison with on-pump coronary artery bypass grafting. | |
| | |
MedLine Citation:
|
PMID: 16308593 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: The authors sought to examine in-hospital and one-year outcomes of off-pump coronary artery bypass grafting (CABG) and to determine the subgroups of patients most likely to benefit from the off-pump procedure in a regular surgical practice. METHODS: From March 2001 to December 2002, 1657 consecutive patients were treated with off-pump CABG and 1693 consecutive patients were treated with on-pump CABG. Propensity score modelling was performed to control for treatment and selection bias. A propensity-matched analysis was performed to identify factors associated with survival benefit from the off-pump procedure. RESULTS: The mortality was similar postoperatively and at one year after surgery. The rate of stroke was decreased in the off-pump group postoperatively (OR=0.49, 95% CI 0.23 to 1.06) and significantly at one year after surgery (OR=0.49, 95% CI 0.27 to 0.90). A significant reduction in acute renal dialysis and a significant increase in myocardial infarction rates were seen in off-pump patients during the initial hospitalization but these differences disappeared during the follow-up period. The number of grafts completed was significantly lower in off-pump CABG than in on-pump CABG (2.62+/-1.00 versus 3.36+/-0.92, respectively; P<0.001). Hospital length of stay and the percentage of patients who required mechanical ventilation were significantly lower in the off-pump group than in the on-pump group. At one year after surgery, the adjusted rate of coronary angiogram and revascularization was similar between the two groups, and the adjusted rate of self-reported angina and memory status was significantly better in the off-pump CABG group. Almost all subgroups of patients had a neutral effect or a survival benefit with the off-pump technique. CONCLUSIONS: The results from a Canada-wide multicentre registry showed the safety and effectiveness of off-pump CABG in most subgroups of patients in a regular surgical practice. |
| | |
Authors:
|
A Lamy; Forough Farrokhyar; Rosanne Kent; Xiaoyin Wang; Kelly M Smith; John C Mullen; Michel Carrier; Anson Cheung; Richard Baillot; |
Related Documents
:
|
19346013 - Myocardial metabolism assessed by microdialysis: a prospective randomized study in on- ... 16607063 - Changes in serum electrolyte levels and their influence on the incidence of atrial fibr... 10958713 - Initial experience with the transurethral self-detachable balloon system for urinary in... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: The Canadian journal of cardiology Volume: 21 ISSN: 0828-282X ISO Abbreviation: Can J Cardiol Publication Date: 2005 Nov |
Date Detail:
|
Created Date: 2005-11-25 Completed Date: 2006-01-20 Revised Date: 2008-04-09 |
Medline Journal Info:
|
Nlm Unique ID: 8510280 Medline TA: Can J Cardiol Country: Canada |
Other Details:
|
Languages: eng Pagination: 1175-81 Citation Subset: IM |
Affiliation:
|
McMaster University, Hamilton, Canada. lamya@mcmaster.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Canada Coronary Artery Bypass* / mortality Coronary Artery Bypass, Off-Pump* / mortality Hospital Mortality Humans Length of Stay Registries Respiration, Artificial Survival Analysis Treatment Outcome |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Impact of diabetes on 12-month outcomes following coronary artery bypass graft surgery: results from...
Next Document: Coronary angioplasty in the acute phase of a myocardial infarction on a myocardial bridge