Document Detail


Can venlafaxine in breast milk attenuate the norepinephrine and serotonin reuptake neonatal withdrawal syndrome.
MedLine Citation:
PMID:  16776907     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A newborn infant whose mother had used venlafaxine, a selective inhibitor of both norepinephrine and serotonin reuptake, throughout pregnancy exhibited signs consistent with the norepinephrine and serotonin reuptake withdrawal syndrome. Is it possible that mother's milk can help mitigate the effects of norepinephrine and serotonin reuptake withdrawal? Pharmacokinetic analysis and review of the only published case with active treatment of a baby with venlafaxine suggest that breastfeeding may mitigate the neonatal withdrawal syndrome.
Authors:
Gideon Koren; Myla Moretti; Bhushan Kapur
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Publication Detail:
Type:  Case Reports; Clinical Conference; Journal Article    
Journal Detail:
Title:  Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstétrique et gynécologie du Canada : JOGC     Volume:  28     ISSN:  1701-2163     ISO Abbreviation:  J Obstet Gynaecol Can     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-06-16     Completed Date:  2006-07-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101126664     Medline TA:  J Obstet Gynaecol Can     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  299-302     Citation Subset:  IM    
Affiliation:
The Motherisk Program, Hospital for Sick Children, Toronto ON, USA.
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MeSH Terms
Descriptor/Qualifier:
Breast Feeding*
Cyclohexanols / administration & dosage,  adverse effects*
Diagnosis, Differential
Female
Humans
Infant, Newborn
Neonatal Abstinence Syndrome / diagnosis*,  etiology,  pathology,  therapy
Pregnancy
Serotonin Uptake Inhibitors / administration & dosage,  adverse effects*
Chemical
Reg. No./Substance:
0/Cyclohexanols; 0/Serotonin Uptake Inhibitors; 93413-69-5/venlafaxine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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