Document Detail

Can technetium-labelled millimicrospheres be used to measure Kupffer-cell function? An experimental study.
MedLine Citation:
PMID:  4006979     Owner:  NLM     Status:  MEDLINE    
It has been suggested that sodium pertechnetate 99mTc millimicrospheres can be used to measure Kupffer-cell function. We studied animals and humans to show whether the clearance and catabolism of 99mTc-labelled millimicrospheres can be used as a measure of Kupffer-cell function. Comparison with albumin 125I-microaggregates clearance of human serum albumin failed to demonstrate that they can be used for this purpose. We suggest that their blood clearance is mainly an expression of liver blood flow.
H J Pearson; J Chamberlain; J Anderson; V Bowry; P R Bell
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  European journal of nuclear medicine     Volume:  10     ISSN:  0340-6997     ISO Abbreviation:  Eur J Nucl Med     Publication Date:  1985  
Date Detail:
Created Date:  1985-08-09     Completed Date:  1985-08-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7606882     Medline TA:  Eur J Nucl Med     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  358-61     Citation Subset:  IM    
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MeSH Terms
Kupffer Cells / physiology*
Propionibacterium acnes / immunology
Rats, Inbred Strains
Serum Albumin, Radio-Iodinated / diagnostic use
Technetium Tc 99m Aggregated Albumin / diagnostic use*
Reg. No./Substance:
0/Serum Albumin, Radio-Iodinated; 0/Technetium Tc 99m Aggregated Albumin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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