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Can 'single use negative pressure wound therapy' be an alternative method to manage keloid scarring? A preliminary report of a clinical and ultrasound/colour-power-doppler study.
MedLine Citation:
PMID:  22716191     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Keloid scarring represents a pathological healing where primary healing phenomenon is deviated from normal. Pico is a single use negative pressure wound therapy system originally introduced to manage open or just closed wounds. Pico dressing is made of silicone, and distributes an 80 mmHg negative pressure across wound bed. Combination of silicon layer and continuous compression could be a valid method to manage keloid scarring. Since November 2011, three patients were enrolled and evaluated before negative pressure treatment, at end of treatment (1 month) and 2 months later, through Vancouver Scar Scale (VSS), Visual Analog Scale (VAS) and a scoring system for itching. Ultrasound (US) and colour-power-doppler (CPD) examination was performed to evaluate thickness and vascularisation of the scar. One patient was discharged from study after 1 week. In last two patients, VSS, VAS and itching significantly improved after 1 month therapy and the results were stable after 2 months without any therapy. At end of therapy, the 'appearance of palisade vessels' disappeared in both cases at CPD exam; US showed a thickness reduction (average 43·8%). We propose a well-tolerated, non invasive treatment to manage keloid scarring. Prospective studies are necessary to investigate whether these preliminary observations are confirmed.
Authors:
Marco Fraccalvieri; Antonino Sarno; Stefano Gasperini; Enrico Zingarelli; Raffaella Fava; Marco Salomone; Stefano Bruschi
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-21
Journal Detail:
Title:  International wound journal     Volume:  -     ISSN:  1742-481X     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101230907     Medline TA:  Int Wound J     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Authors. International Wound Journal © 2012 Blackwell Publishing Ltd and Medicalhelplines.com Inc.
Affiliation:
M Fraccalvieri, MD, Department of Plastic Reconstructive and Aesthetic Surgery, University of Turin, San Giovanni Battista Hospital, Turin, Italy A Sarno, MD, Radiology Unit, Giovanni Battista Hospital, Turin, Italy S Gasperini, MD, SIRTES: International school of wound repair, University of Pisa, Pisa, Italy E Zingarelli, MD, Department of Plastic Reconstructive and Aesthetic Surgery, University of Turin, San Giovanni Battista Hospital, Turin, Italy R Fava, MD, ASLT05, Local Health Unit of Moncalieri, Turin, Italy M Salomone, MD, Department of Plastic Reconstructive and Aesthetic Surgery, University of Turin, San Giovanni Battista Hospital, Turin, Italy S Bruschi, MD, Department of Plastic Reconstructive and Aesthetic Surgery, University of Turin, San Giovanni Battista Hospital, Turin, Italy.
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