| Can a single, early quantitative human chorionic gonadotropin measurement in an in vitro fertilization-gamete intrafallopian transfer program predict pregnancy outcome? | |
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MedLine Citation:
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PMID: 1633905 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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STUDY OBJECTIVE: To assess the predictive value of a single serum human chorionic gonadotropin (hCG) measurement obtained on day 14, 15, or 16 after transfer in in vitro fertilization or gamete intrafallopian transfer pregnancies. DESIGN: Retrospective. SETTING: Assisted reproductive technology (ART) programs. PATIENTS: One hundred thirty-four consecutive pregnancies from two ART programs were reviewed. RESULTS: The incidence of livebirth was only 6% when day 14 to 16 hCG values were less than 100 mIU/mL, but increased to 82% with levels greater than 100 mIU/mL (P less than 0.001). The incidence of livebirth and multiple birth correlated with rising hCG levels. Only 1% (1/71) of pregnancies with serum hCG values greater than 100 mIU/mL was ectopic, and this case was a bilateral (double) ectopic. CONCLUSIONS: A single serum hCG measurement obtained 14 to 16 days after embryo or gamete transfer not only is diagnostic but also has good predictive value for pregnancy outcome. |
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Authors:
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J S Heiner; J F Kerin; L L Schmidt; T C Wu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Fertility and sterility Volume: 58 ISSN: 0015-0282 ISO Abbreviation: Fertil. Steril. Publication Date: 1992 Aug |
Date Detail:
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Created Date: 1992-08-25 Completed Date: 1992-08-25 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0372772 Medline TA: Fertil Steril Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 373-7 Citation Subset: IM |
Affiliation:
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University of California-Los Angeles (UCLA), School of Medicine. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Chorionic Gonadotropin
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blood* Female Fertilization in Vitro* Gamete Intrafallopian Transfer* Humans Pregnancy Pregnancy Outcome* Retrospective Studies Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Chorionic Gonadotropin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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