Document Detail

Can regional strain and strain rate measurement be performed during both dobutamine and exercise echocardiography, and do regional deformation responses differ with different forms of stress testing?
MedLine Citation:
PMID:  12712011     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Regional strain (epsilon) and strain rate (SR) measurement could be the optimal approach to quantifying stress echocardiography images. However, signal noise could preclude their use. Study aims Our aim was to compare the feasibility of regional peak systolic (p) velocity (Vel), pSR/epsilon measurement, and their normal responses during upright (group 1, n = 10) and supine (group 2, n = 10) bicycle exercise and (group 3, n = 10) dobutamine stress. METHODS: For each type of stress study, pVel/pSR/epsilon data were acquired at baseline, low (100-120 bpm), and peak (140-160 bpm) heart rate (HR); and during recovery. RESULTS: During dobutamine pVel/pSR/epsilon were interpretable in >95% of segments at every stress stage, whereas in groups 1 and 2 pSR/epsilon responses were noninterpretable in >36% of segments (P <.0002). The highest proportions of data exclusions were from the lateral and anterior walls. In all groups, regional systolic pVel and SR values increased linearly and reached maximal value at peak HR (P <.0006 vs baseline). Pepsilon showed a biphasic response, initially increasing at low HR, and then remaining constant or falling at peak HR. CONCLUSION: PSR/pepsilon quantification of stress echocardiography may currently be restricted to dobutamine as increased signal noise precludes adequate data acquisition during exercise. For all forms of stress both pSR and pVel increased linearly, whereas pepsilon response was biphasic as a result of the reduced filling at higher HRs.
Giedrius Davidavicius; Miroslaw Kowalski; R Ian Williams; Jan D'hooge; Giovanni Di Salvo; Gilbert Pierre-Justin; Piet Claus; Frank Rademakers; Marie-Christine Herregods; Alan G Fraser; Luc A Pierard; Bart Bijnens; George R Sutherland
Publication Detail:
Type:  Comparative Study; Evaluation Studies; Journal Article    
Journal Detail:
Title:  Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography     Volume:  16     ISSN:  0894-7317     ISO Abbreviation:  J Am Soc Echocardiogr     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2003-04-24     Completed Date:  2003-09-16     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  8801388     Medline TA:  J Am Soc Echocardiogr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  299-308     Citation Subset:  IM    
Department of Cardiology, University Hospital Gasthuisberg, Leuven, Belgium.
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MeSH Terms
Blood Pressure
Coronary Disease / physiopathology,  ultrasonography*
Echocardiography, Stress / methods*
Exercise Test*
Feasibility Studies
Heart Rate
Middle Aged
Reproducibility of Results

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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