Document Detail


Can plant oncogenes inhibit programmed cell death? The rolB oncogene reduces apoptosis-like symptoms in transformed plant cells.
MedLine Citation:
PMID:  22899080     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The rolB oncogene was previously identified as an important player in ROS metabolism in transformed plant cells. Numerous reports indicate a crucial role for animal oncogenes in apoptotic cell death. Whether plant oncogenes such as rolB can induce programmed cell death (PCD) in transformed plant cells is of particular importance. In this investigation, we used a single-cell assay based on confocal microscopy and fluorescent dyes capable of discriminating between apoptotic and necrotic cells. Our results indicate that the expression of rolB in plant cells was sufficient to decrease the proportion of apoptotic cells in steady-state conditions and diminish the rate of apoptotic cells during induced PCD. These data suggest that plant oncogenes, like animal oncogenes, may be involved in the processes mediating PCD.
Authors:
Tatiana Y Gorpenchenko; Dmitry L Aminin; Yuliya V Vereshchagina; Yuri N Shkryl; Galina N Veremeichik; Galina K Tchernoded; Victor P Bulgakov
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-08-17
Journal Detail:
Title:  Plant signaling & behavior     Volume:  7     ISSN:  1559-2324     ISO Abbreviation:  Plant Signal Behav     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-11-16     Completed Date:  2013-04-25     Revised Date:  2013-07-12    
Medline Journal Info:
Nlm Unique ID:  101291431     Medline TA:  Plant Signal Behav     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1058-61     Citation Subset:  IM    
Affiliation:
Institute of Biology and Soil Science; Far East Branch of Russian Academy of Sciences; Vladivostok, Russia.
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MeSH Terms
Descriptor/Qualifier:
Agrobacterium
Apoptosis / genetics*
Gene Expression*
Genes, Plant
Microscopy, Confocal
Necrosis
Oncogenes*
Plant Cells / physiology*
Reactive Oxygen Species / metabolism*
Rubia / genetics*,  physiology
Transformation, Genetic*
Chemical
Reg. No./Substance:
0/Reactive Oxygen Species
Comments/Corrections

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