Document Detail

Can a patient be successfully prepared for pheochromocytoma surgery in three days? A case report.
MedLine Citation:
PMID:  17468737     Owner:  NLM     Status:  MEDLINE    
The case of a patient who insisted on urgent surgical removal of a pheochromocytoma is presented. Rapid preparation started with continuous infusion of urapidil 3 days before surgery. On the evening before the operation, an additional infusion of magnesium sulphate was started. The target of preoperative optimization was to maintain blood pressure <140/90 mm Hg and heart rate <100 beats min(-l). Anesthesia was induced with fentanyl, propofol and rocuronium and maintained with sevoflurane in 100% oxygen and continuous infusion of fentanyl. Hypertensive events were treated by continuous infusions of urapidil and magnesium sulphate. Just before tumor resection, additional boluses of urapidil and MgSO4 were administered; both fentanyl infusion and end tidal concentration of sevoflurane were increased. Blood pressure was well maintained through the anesthesia; no transient periods of hypotension after tumor removal were observed. The patient's peroperative course was uneventful. He was discharged home without antihypertensive medication on the 5th postoperative day. This case demonstrates that with urapidil and magnesium sulphate administration rapid preparation for pheochromocytoma resection can be successfully achieved within 3 days.
R J Jankovic; S M Konstantinovic; D J Milic; D S Mihailovic; B S Stosic
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Minerva anestesiologica     Volume:  73     ISSN:  0375-9393     ISO Abbreviation:  Minerva Anestesiol     Publication Date:  2007 Apr 
Date Detail:
Created Date:  2007-04-30     Completed Date:  2007-08-22     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0375272     Medline TA:  Minerva Anestesiol     Country:  Italy    
Other Details:
Languages:  eng     Pagination:  245-8     Citation Subset:  IM    
Department of Anesthesia and Intensive Care, University Clinical Center, Nish, Serbia and Montenegro.
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MeSH Terms
Adrenal Gland Neoplasms / surgery*
Adrenergic alpha-Antagonists / therapeutic use
Blood Pressure / physiology
Catecholamines / urine
Heart Rate / physiology
Magnesium Sulfate / therapeutic use
Pheochromocytoma / surgery*
Piperazines / therapeutic use
Preoperative Care
Reg. No./Substance:
0/Adrenergic alpha-Antagonists; 0/Catecholamines; 0/Piperazines; 34661-75-1/urapidil; 7487-88-9/Magnesium Sulfate

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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