Document Detail


Can ophthalmologists correctly identify patients defaulting from pilocarpine therapy?
MedLine Citation:
PMID:  3706456     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We determined whether clinical measurements and assessments available to ophthalmologists could be used to identify patients who default from pilocarpine treatment. The measurements and assessments included intraocular pressure, pupillary diameter, pupillary reactivity to light, the patient's report of compliance, the physician's prediction of compliance, the patient's log of pilocarpine administration, and the weight of pilocarpine eyedrops utilized. Compliance with the pilocarpine regimen was measured with an unobtrusive eyedrop medication monitor. Intraocular pressure and pupillary diameter did not correlate with compliance to the regimen as measured by the eyedrop monitor. Pupillary reaction to light, the physician's prediction of compliance, a daily log of pilocarpine administration, the weight of pilocarpine utilized, and the patient's report of compliance correlated modestly with compliance as measured by the monitor (range of correlations, 0.19 to 0.24). However, none of these measures taken by itself or combined in any manner adequately distinguished patients with lower rates of compliance from those with higher rates of compliance. At present, the eyedrop monitor is the only reliable method for detecting patients who default from treatment.
Authors:
M A Kass; M Gordon; D W Meltzer
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of ophthalmology     Volume:  101     ISSN:  0002-9394     ISO Abbreviation:  Am. J. Ophthalmol.     Publication Date:  1986 May 
Date Detail:
Created Date:  1986-06-12     Completed Date:  1986-06-12     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0370500     Medline TA:  Am J Ophthalmol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  524-30     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Glaucoma / drug therapy*
Humans
Ophthalmology
Patient Compliance*
Physician's Role
Pilocarpine / administration & dosage*,  therapeutic use
Grant Support
ID/Acronym/Agency:
EY 02687/EY/NEI NIH HHS; EY 03579/EY/NEI NIH HHS
Chemical
Reg. No./Substance:
92-13-7/Pilocarpine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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