Document Detail

Can a multimodal mind-body program enhance the treatment effects of physical activity in breast cancer survivors with chronic tumor-associated fatigue? A randomized controlled trial.
MedLine Citation:
PMID:  23766391     Owner:  NLM     Status:  MEDLINE    
PATIENTS AND METHODS: Sixty-four women (mean age = 56.7 years) suffering from chronic fatigue after active tumor treatment were randomly assigned to either an experimental or a control (n = 32 each) intervention (10 weeks). Fatigue, quality of life (QoL), functional well-being, anxiety, and depression were measured with standard questionnaires at baseline, after 10 weeks, and after 3 months.
RESULTS: Compared with baseline, both groups had reduced fatigue scores after treatment without any significant difference between groups (posttreatment, Δ = -0.3, confidence interval = -1.6 to 1.0, P = .678; follow-up, Δ = -0.4, confidence interval = -1.8 to 0.9, P = .510). All patients also improved regarding QoL and general functional well-being.
CONCLUSION: Since both interventions reduced fatigue symptoms and enhanced QoL to a similar extent, we observed no verifiable add-on effect of the MMMT regarding fatigue symptoms. Considering the higher costs with additional expenditure related to MMMT, home-based walking intervention is recommended.
Günther Spahn; Kyung-Eun Choi; Charlotte Kennemann; Rainer Lüdtke; Ulla Franken; Jost Langhorst; Anna Paul; Gustav J Dobos
Publication Detail:
Type:  Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Integrative cancer therapies     Volume:  12     ISSN:  1552-695X     ISO Abbreviation:  Integr Cancer Ther     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-14     Completed Date:  2014-01-24     Revised Date:  2014-07-31    
Medline Journal Info:
Nlm Unique ID:  101128834     Medline TA:  Integr Cancer Ther     Country:  United States    
Other Details:
Languages:  eng     Pagination:  291-300     Citation Subset:  IM    
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MeSH Terms
Breast Neoplasms / therapy*
Chronic Disease
Combined Modality Therapy
Fatigue / etiology*,  therapy*
Middle Aged
Mind-Body Therapies*
Motor Activity*
Quality of Life
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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