| Can morels (Morchella sp.) induce a toxic neurological syndrome? | |
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MedLine Citation:
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PMID: 20507248 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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INTRODUCTION: Several cases of morel poisoning associated with neurological symptoms have been reported. The objective of this study was to describe this new mushroom poisoning syndrome. MATERIAL AND METHODS: Retrospective study of morel poisonings collected in the French Poison Control Centers from 1976 to 2006. Cases were classified as neurological syndrome (NS; tremor or dizziness/inebriation or unsteadiness/ataxia +/- associated with gastrointestinal symptoms) or isolated gastrointestinal syndrome. RESULTS: 146 patients presented gastrointestinal syndrome (median time to onset: 5 h) and 129 presented NS (12 h) after morel consumption. Gastrointestinal (67%) and other neurological symptoms were also present (mainly ocular/vision disorders: 26%, paresthesia: 7%, drowsiness/confusion: 6%, and muscle disorders: 6%). These patients more frequently ingested a large quantity of morels. Confusion with Gyromitra was ruled out. DISCUSSION: The NS is very different from the common gastrointestinal syndrome occurring after ingestion of poorly cooked morels and is not limited to a cerebellar syndrome. |
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Authors:
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Philippe Saviuc; Patrick Harry; Corine Pulce; Robert Garnier; Amandine Cochet |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Clinical toxicology (Philadelphia, Pa.) Volume: 48 ISSN: 1556-9519 ISO Abbreviation: Clin Toxicol (Phila) Publication Date: 2010 May |
Date Detail:
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Created Date: 2010-05-28 Completed Date: 2010-06-22 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101241654 Medline TA: Clin Toxicol (Phila) Country: England |
Other Details:
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Languages: eng Pagination: 365-72 Citation Subset: AIM; IM |
Affiliation:
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Toxicovigilance Center, Michallon Hospital, Grenoble, France. PSaviuc@chu-grenoble.fr <PSaviuc@chu-grenoble.fr> |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Ascomycota* Gastrointestinal Diseases / chemically induced, epidemiology Humans Middle Aged Mushroom Poisoning / diagnosis, epidemiology* Mycotoxins / toxicity* Nervous System Diseases / chemically induced*, epidemiology Retrospective Studies Syndrome |
| Chemical | |
Reg. No./Substance:
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0/Mycotoxins |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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