| Can misoprostol reduce blood loss in laparoscopy-assisted vaginal hysterectomy? | |
| | |
MedLine Citation:
|
PMID: 21631445 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
|
Background: Intraoperative blood loss is a concern in the surgical treatment of myomatous uteri. Misoprostol causes the myometrium and isolated uterine arteries to contract and has blood-saving effects in myomectomy. Aim: To assess the efficacy of rectal misoprostol in reducing haemorrhage during laparoscopy-assisted vaginal hysterectomy (LAVH). Methods: Retrospective case-control study. Women who had undergone LAVH for leiomyoma were enrolled (n = 117). Forty-nine women who used 400 μg of misoprostol rectally 1 h before LAVH were compared with 68 women who did not. The surgical outcomes were compared statistically with Mann-Whitney rank sum test, χ(2) test, or Fisher's exact test. Results: The demographic variables were similarly distributed in both groups. There were no significant differences in the estimated blood loss, reduction in haemoglobin, operation time, or uterine weight between the two groups (P > 0.05). The rates of operative complications (4.1 vs 10.3% for the misoprostol and control groups, respectively, P = 0.21) were not different. There was no febrile morbidity (>38°C) within 24 h of the misoprostol insertion. Conclusion: These data do not support the use of rectal misoprostol to reduce blood loss during LAVH. The pharmacoclinical effects of misoprostol in the uterus should be clarified. |
| | |
Authors:
|
Hyun Park; Bo S Yoon; Seok J Seong; Ji Y Kim; Jeong Y Shim; Chong T Park |
Related Documents
:
|
11181925 - Drug-induced hemodynamic perturbations alter the disposition of markers of blood volume... 3947835 - The fractional distribution of the cardiac output in man using microspheres labelled wi... 2476615 - Hemodynamic effects of a poly(ethylene oxide) drag-reducing polymer, polyox wsr n-60k, ... 3840585 - The contractility and performance of the preterm left ventricle before and after early ... 21874475 - Cerebral perfusion mri in mice. 17996105 - Signs of oral dryness in relation to salivary flow rate, ph, buffering capacity and dry... |
Publication Detail:
|
Type: Journal Article Date: 2011-03-29 |
Journal Detail:
|
Title: The Australian & New Zealand journal of obstetrics & gynaecology Volume: 51 ISSN: 1479-828X ISO Abbreviation: Aust N Z J Obstet Gynaecol Publication Date: 2011 Jun |
Date Detail:
|
Created Date: 2011-06-02 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0001027 Medline TA: Aust N Z J Obstet Gynaecol Country: Australia |
Other Details:
|
Languages: eng Pagination: 248-51 Citation Subset: IM |
Copyright Information:
|
© 2011 The Authors. Australian and New Zealand Journal of Obstetrics and Gynaecology © 2011 The Royal Australian and New Zealand College of Obstetricians and Gynaecologists. |
Affiliation:
|
Department of Obstetrics and Gynecology Department of Pathology, Kangnam CHA Hospital, College of Medicine, CHA University, Seoul, Korea. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Clinical manifestations in women with isolated fallopian tubal torsion; a rare but important entity.
Next Document: Analysis of factors predicting success of metformin and clomiphene treatment for women with infertil...