Document Detail


Can measurement of mixed venous oxygen saturation replace measurement of cardiac output in patients with advanced heart failure?
MedLine Citation:
PMID:  9740888     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Nursing care of patients with advanced heart failure with low ejection fraction requires strict management of IV fluids. Measurement of mixed venous oxygen saturation offers advantages over measurement of cardiac output because no administration of fluid is required and data are obtained continuously. OBJECTIVES: To determine the relationship between mixed venous oxygen saturation and cardiac output in patients with advanced heart failure who have low ejection fraction and to determine if use of vasoactive medications alters the relationship between mixed venous oxygen saturation and cardiac output. METHODS: Simultaneously obtained measurements of mixed venous oxygen saturation and cardiac output were compared in 42 patients with advanced heart failure with ejection fractions of 30% or less (mean, 19.5%). RESULTS: Correlation between mixed venous oxygen saturation and cardiac output was r = 0.54 (P < .001). For subjects not receiving vasoactive medications (n = 28), r = 0.52 (P = .004); for those receiving vasoactive medications (n = 14), r = 0.57 (P = .03). CONCLUSIONS: Similar correlations in the groups receiving and not receiving vasoactive medications suggest that even with pharmacological support, changes in mixed venous oxygen saturation may not be reflected by concomitant changes in cardiac output. Measurement of mixed venous oxygen saturation should not replace measurement of cardiac output for clinical decision making in patients with advanced heart failure with low ejection fraction.
Authors:
A Gawlinski
Related Documents :
3141908 - Continuous wave doppler cardiac output: use in pediatric patients receiving inotropic s...
1551268 - Morphologic aspects of pericardial heart disease: part i.
18984988 - Development of left ventricular apical akinesis and thrombus during pericardiocentesis ...
2015318 - Perioperative myocardial infarction.
25393318 - The role of the mptp in conditioning the heart - translatability and mechanism.
2365528 - Cross-sectional echocardiography in the diagnosis of atrioventricular septal defect.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  American journal of critical care : an official publication, American Association of Critical-Care Nurses     Volume:  7     ISSN:  1062-3264     ISO Abbreviation:  Am. J. Crit. Care     Publication Date:  1998 Sep 
Date Detail:
Created Date:  1998-11-12     Completed Date:  1998-11-12     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  9211547     Medline TA:  Am J Crit Care     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  374-80; quiz 381-2     Citation Subset:  IM; N    
Affiliation:
University of California, Los Angeles, Medical Center, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aged, 80 and over
Cardiac Output*
Cardiovascular Agents / therapeutic use
Female
Heart Failure / drug therapy,  metabolism*,  nursing,  physiopathology*
Humans
Male
Middle Aged
Monitoring, Physiologic / methods
Oximetry / methods*
Oxygen / blood*
Oxygen Consumption
Reproducibility of Results
Sensitivity and Specificity
Stroke Volume
Grant Support
ID/Acronym/Agency:
NR 06698-03/NR/NINR NIH HHS
Chemical
Reg. No./Substance:
0/Cardiovascular Agents; 7782-44-7/Oxygen

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Clinical evaluation of noninvasive monitoring of oxygen saturation in critically ill patients.
Next Document:  Impact of family demands and family strengths and capabilities on family well-being and adaptation a...