Document Detail

Can intense exercise contribute to cardiovascular disease?
MedLine Citation:
PMID:  19804216     Owner:  NLM     Status:  In-Data-Review    
Aerobic exercise is associated with a number of beneficial effects, including reduction in cardiovascular morbidity and mortality, decreased blood pressure, improved insulin sensitivity, weight loss and favorable alterations in lipids. However, intense exercise may have significant deleterious cardiovascular effects. Excessive physical activity may cause increased oxidative stress with resultant endothelial dysfunction and progressive atherosclerosis. Furthermore, intense exercise may promote exercise-induced hypertension that is also associated with endothelial dysfunction and increased cardiovascular mortality. The purpose of this article is to summarize our current understanding of whether intense exercise can contribute to the development of cardiovascular disease.
Farhan Majeed; Michael Miller
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Future cardiology     Volume:  3     ISSN:  1744-8298     ISO Abbreviation:  Future Cardiol     Publication Date:  2007 May 
Date Detail:
Created Date:  2009-10-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101239345     Medline TA:  Future Cardiol     Country:  England    
Other Details:
Languages:  eng     Pagination:  243-8     Citation Subset:  -    
University of Maryland Medical Center, Division of Cardiology, 22 South Greene Street, Room G3K18, Baltimore, MD 21201, USA.
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