| Can hyperbaric oxygenation therapy (HOT) modify the blood testosterone concentration? | |
| | |
MedLine Citation:
|
PMID: 20890859 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
INTRODUCTION: Testosterone has a modulating effect on inflammatory and healing processes. In this study, we evaluate whether hyperbaric oxygenation therapy (HOT) modifies the blood concentration of total testosterone (TT) in patients treated for different pathologies. MATERIALS AND METHODS: Fourteen male patients (23-72 years old) were treated with 90-min HOT sessions (range 4 to 23 sessions) as an adjuvant to the following conditions: leg fractures, osteonecrosis, diabetic foot, firearm injuries, complicated arthroprosthesis and underwater diving embolism. As controls, six healthy male volunteers (37-51 years old) were subjected to 10 HOT sessions. Testosterone plasma levels were determined immediately before the first HOT session and the day after the last session. RESULTS: At the end of treatment, 12 patients fully recovered and 2 (diabetic foot patients) showed a marked improvement. Testosterone significantly increased after hyperbaric oxygenation therapy in both patients and controls (ANOVA, p<0.004). DISCUSSION: We conclude that hyperbaric oxygenation therapy increases the blood concentration of total testosterone in patients as well as in healthy men. This finding raises new questions and indicates the need to investigate the causes of this increase and its therapeutic significance. Since testosterone modulates inflammation and healing processes, it is possible that hormonal changes are the mechanisms affected by hyperbaric oxygenation therapy. |
| | |
Authors:
|
G Passavanti; P Tanasi; M Brauzzi; M R Pagni; A M Aloisi |
Related Documents
:
|
7089649 - Septic shock and the obstetrician/gynecologist. 8449089 - Mixed venous oxygen saturation in critically ill septic shock patients. the role of def... 2916389 - Right ventricular dysfunction in septic shock: assessment by measurements of right vent... 19481869 - The effects of topical epinephrine on haemodynamics and markers of tissue perfusion in ... 21585169 - Nephrolithiasis in medullary sponge kidney. 6532409 - Study of makeshift hospital during cholera outbreak. 17039989 - Development of wernicke encephalopathy in a terminally ill cancer patient consuming an ... 292969 - Bone marrow karyotypes of children with nonlymphocytic leukemia. 12359819 - Paroxysmal nonepileptic events in children and adolescents. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Urologia Volume: 77 ISSN: 0391-5603 ISO Abbreviation: Urologia Publication Date: 2010 Jan-Mar |
Date Detail:
|
Created Date: 2010-10-04 Completed Date: 2011-02-01 Revised Date: 2011-02-02 |
Medline Journal Info:
|
Nlm Unique ID: 0417372 Medline TA: Urologia Country: Italy |
Other Details:
|
Languages: eng Pagination: 52-6 Citation Subset: IM |
Affiliation:
|
Dpt of Urology Misericordia Hospital Grosseto, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Humans Hyperbaric Oxygenation* Male Middle Aged Testosterone / blood* Young Adult |
| Chemical | |
Reg. No./Substance:
|
58-22-0/Testosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: [Associating Serenoa repens, Urtica dioica and Pinus pinaster. Safety and efficacy in the treatment ...
Next Document: [Laparoscopic radical prostatectomy without ligation of the Santorini's venous plexus].