| Can dietary fructans lower serum glucose? | |
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MedLine Citation:
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PMID: 21040500 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background: Convincing evidence indicates that the consumption of inulin-type fructans, inulin, and oligofructose has beneficial effects on blood glucose changes in animal models, although data in humans have been considered equivocal. As such, a systematic review of available literature on humans was conducted to evaluate the effectiveness of dietary inulin-type fructans on serum glucose. Methods: Thirteen eligible randomized controlled trials (RCT), published from 1984 to 2009, were identified using a comprehensive search strategy involving the PubMed, Medline, and Cochrane Library databases. Exclusion criteria, such as the absence of a control group, lack of information on the quantity of inulin-type fructans used, and lack of glucose values at outcome, were established. Results: Upon review, only four of the 13 trials (31%) showed a decrease in serum glucose concentration and only one of these was statistically significant. The remaining nine trials showed no significant changes in serum glucose concentration. Conclusion: Based on the present systematic review, it does not appear that inulin-type fructans have a significant lowering effect on serum glucose in humans. More RCT are needed to determine whether inulin-type fructans, inulin, and oligofructose have beneficial effects on blood glucose in humans. |
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Authors:
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Nana K A Bonsu; C Shanthi Johnson; Katherine M McLeod |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of diabetes Volume: 3 ISSN: 1753-0407 ISO Abbreviation: J Diabetes Publication Date: 2011 Mar |
Date Detail:
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Created Date: 2011-02-21 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101504326 Medline TA: J Diabetes Country: Australia |
Other Details:
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Languages: eng Pagination: 58-66 Citation Subset: IM |
Copyright Information:
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© 2011 Ruijin Hospital, Shanghai Jiaotong University School of Medicine and Blackwell Publishing Asia Pty Ltd. |
Affiliation:
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Program in Gerontology Faculty of Kinesiology & Health Studies Saskatchewan Population Health and Evaluation Research Unit, University of Regina, Saskatchewan, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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