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Can birth weight predict later body composition in anorexia nervosa?
MedLine Citation:
PMID:  22378228     Owner:  NLM     Status:  Publisher    
BACKGROUND/OBJECTIVES:The relationship between birth weight and body composition at later stages in life was not studied previously in anorexia nervosa (AN). The aim of the following brief report is to present results concerning the relationship between birth weight and later body composition specifically in AN, and to check if the programming of body composition from birth weight is still detected in severely emaciated AN patients.SUBJECTS/METHODS:One hundred and fifty-one female AN patients aged between 13 and 44 were recruited from 11 inpatient treatment facilities in France. Birth weight, body weight and height were obtained. Body composition was measured using bioelectrical impedance. Birth weight was significantly correlated to lifetime maximum body mass index (BMI; r=0.211, P=0.009) and significantly correlated to fat-free mass index (r=0.190, P=0.027) but not to fat mass index (FMI).RESULTS:This report confirms that even in AN when patients are severely emaciated and where fat-free mass (FFM) and fat mass (FM) are low, a link between birth weight and FFM and BMI can still be identified, independently from age.CONCLUSION:Further studies are needed on larger samples exploring other factors, such as gender, puberty and ethnicity.European Journal of Clinical Nutrition advance online publication, 29 February 2012; doi:10.1038/ejcn.2012.21.
L Mattar; C Pichard; N Godart; J-C Melchior
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-2-29
Journal Detail:
Title:  European journal of clinical nutrition     Volume:  -     ISSN:  1476-5640     ISO Abbreviation:  -     Publication Date:  2012 Feb 
Date Detail:
Created Date:  2012-3-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8804070     Medline TA:  Eur J Clin Nutr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
1] INSERM U669, Maison de Solenn, Paris, France [2] Université Paris-Sud and Université Paris Descartes, Paris, France [3] Psychiatry Unit, Institut Mutualiste Montsouris 42, Faculté de médecine Paris Descartes, Paris, France.
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