Document Detail

Can atypical antipsychotics improve tardive dyskinesia associated with other atypical antipsychotics? Case report and brief review of the literature.
MedLine Citation:
PMID:  19395427     Owner:  NLM     Status:  MEDLINE    
Tardive dyskinesia (TD) is a devastating adverse effect of long-term antipsychotic drug treatment. Atypical antipsychotics produce less TD, and it has been shown that they may have a therapeutic effect on pre-existing TD. Here, we report a case of olanzapine-induced TD which did not improve after switching to risperidone but improved after the addition of quetiapine to risperidone regimen. We also provide a brief review of the reported cases on TD induced by atypical antipsychotics which improved after switching to another atypical agent. It is unclear whether some atypical antipsychotics are more effective than others in the treatment of TD. Differences in this property and the underlying mechanism require further study.
V Peritogiannis; S Tsouli
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Publication Detail:
Type:  Case Reports; Journal Article     Date:  2009-04-24
Journal Detail:
Title:  Journal of psychopharmacology (Oxford, England)     Volume:  24     ISSN:  1461-7285     ISO Abbreviation:  J. Psychopharmacol. (Oxford)     Publication Date:  2010 Jul 
Date Detail:
Created Date:  2010-06-17     Completed Date:  2010-09-16     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8907828     Medline TA:  J Psychopharmacol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1121-5     Citation Subset:  IM    
Medical School, University of Ioannina, Ioannina 45500, Greece.
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MeSH Terms
Anti-Dyskinesia Agents*
Antipsychotic Agents / adverse effects*,  therapeutic use*
Benzodiazepines / adverse effects,  therapeutic use
Clozapine / adverse effects,  therapeutic use
Dibenzothiazepines / adverse effects,  therapeutic use
Dyskinesia, Drug-Induced / drug therapy*
Risperidone / adverse effects,  therapeutic use
Schizophrenia, Paranoid / complications,  drug therapy
Reg. No./Substance:
0/Anti-Dyskinesia Agents; 0/Antipsychotic Agents; 0/Dibenzothiazepines; 0/quetiapine; 106266-06-2/Risperidone; 12794-10-4/Benzodiazepines; 132539-06-1/olanzapine; 5786-21-0/Clozapine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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