| Can ROTEM thromboelastometry predict postoperative bleeding after cardiac surgery? | |
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MedLine Citation:
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PMID: 18922419 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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OBJECTIVE: To evaluate the predictive ability of ROTEM thromboelastometry (Pentapharm, Basel, Switzerland) to identify patients bleeding more than 200 mL/h in the early postoperative period after cardiac surgery. DESIGN: A prospective observational study. SETTING: A single university hospital. Participants: Fifty-eight adult male and female patients undergoing primary coronary artery revascularization. INTERVENTIONS: Blood samples taken preoperatively and at 1, 2, and 3 hours after surgery. MEASUREMENTS AND MAIN RESULTS: Eight patients bled at least 200 mL/h in the study period. All (100%) had at least 1 abnormal ROTEM result in the study period. Of the 49 patients not found to be bleeding more than 200 mL/h in any of the first 4 postoperative hours, 46 (94%) had at least 1 abnormal ROTEM result. The positive and negative predictive values were 14.8% and 100%, respectively. CONCLUSIONS: ROTEM thromboelastometry has poor predictive utility to identify patients who bleed more than 200 mL/h in the early postoperative period after cardiac surgery. However, its negative predictive value was good. |
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Authors:
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Simon J Davidson; Donovan McGrowder; Michael Roughton; Andrea A Kelleher |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Journal of cardiothoracic and vascular anesthesia Volume: 22 ISSN: 1532-8422 ISO Abbreviation: J. Cardiothorac. Vasc. Anesth. Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-10-16 Completed Date: 2009-01-27 Revised Date: 2010-04-05 |
Medline Journal Info:
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Nlm Unique ID: 9110208 Medline TA: J Cardiothorac Vasc Anesth Country: United States |
Other Details:
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Languages: eng Pagination: 655-61 Citation Subset: IM |
Affiliation:
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Department of Haematology, Royal Bromptom Hospital, London, UK. s.davidson@rbht.nhs.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Coagulation Cardiac Surgical Procedures / adverse effects* Female Humans Male Middle Aged Postoperative Hemorrhage / diagnosis* Prospective Studies Sensitivity and Specificity Thrombelastography / instrumentation* |
| Comments/Corrections | |
Comment In:
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J Cardiothorac Vasc Anesth. 2008 Oct;22(5):653-4
[PMID:
18922418
]
J Cardiothorac Vasc Anesth. 2010 Apr;24(2):381; author reply 381-2 [PMID: 19450990 ] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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