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Can RADS Be Iatrogenic?
MedLine Citation:
PMID:  21457622     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Reactive airways dysfunction syndrome (RADS) is defined as an asthma-like illness which develops after a single high-level exposure to a pulmonary irritant. Two different cases are reviewed in which the exposure circumstances were clearly not sufficient to result in chronic adverse health effects yet resulted in persistent respiratory symptoms and a clinical diagnosis of RADS. Potential explanations for an erroneous diagnosis of RADS are discussed including incomplete exposure assessments, medication side-effects which may contribute to respiratory symptoms, and alternative explanations for respiratory symptoms or test findings. In particular, the empiric use of bronchodilator medications without a clear indication appeared to be a potential contributing factor to continued respiratory symptoms. Without a clear understanding of the reported exposure, the diagnosis of RADS should be carefully considered. The possibility of an iatrogenic sequence of events in which medication side-effects facilitate respiratory symptoms and a mistaken diagnosis of RADS should be considered, particularly in those cases with a poorly defined exposure history.
Authors:
David J Hewitt
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-3-30
Journal Detail:
Title:  Respiratory care     Volume:  -     ISSN:  0020-1324     ISO Abbreviation:  -     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-4-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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