| Can the OSA-18 quality-of-life questionnaire detect obstructive sleep apnea in children? | |
| | |
MedLine Citation:
|
PMID: 20026494 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
BACKGROUND: Polysomnography is the best tool available for diagnosing obstructive sleep apnea (OSA) in children. However, polysomnography is relatively inaccessible and costly, and studies are needed to evaluate other diagnostic approaches. It has been suggested that the OSA-18 quality-of-life questionnaire (OSA-18) is a useful measure that could replace polysomnography. The purpose of our study was to determine if the OSA-18, is an accurate measure for the detection of moderate-to-severe OSA. PATIENTS AND METHODS: Children who were referred to our sleep laboratory for evaluation of suspected OSA and who had a nocturnal pulse oximetry study were included in our cross-sectional study. The results of the oximetry study were interpreted by using the McGill oximetry score (MOS). Abnormal scores were consistent with moderate-to-severe OSA. We analyzed demographic and medical data in addition to the OSA-18 results. We estimated sensitivity and negative predictive values for the OSA-18 to detect an abnormal MOS. We also conducted logistic regression analyses with MOS as the dependent variable and the OSA-18 score, age, gender, comorbidities, and race as independent variables. RESULTS: We studied 334 children (mean age: 4.6 years; 58% male). The OSA-18 had a sensitivity of 40% and a negative predictive value of 73% for detecting an abnormal MOS. While controlling for other variables in the regression model, for each unit increase in the OSA-18 score, the odds of having an abnormal MOS were increased by 2%. For each 1-year increase in age, the odds of having an abnormal MOS were decreased by 17%. CONCLUSIONS: Among children who are referred to a sleep laboratory, the OSA-18 does not accurately detect which children will have an abnormal MOS and cannot be used to exclude moderate-to-severe OSA. The OSA-18 should not be used in the place of objective testing to identify moderate-to-severe OSA in children. |
| | |
Authors:
|
Evelyn Constantin; Ted L Tewfik; Robert T Brouillette |
Related Documents
:
|
23638314 - Relationships between exhaled nitric oxide and atopy profiles in children with asthma. 23586594 - Interactive support interventions for caregivers of asthmatic children. 22952834 - Young children consider merit when sharing resources with others. 7784794 - Chronic nasal obstruction in children. a fiberscopic study. 15773884 - Traumatic injuries to the teeth in young individuals with cerebral palsy. 18248534 - Between- and within-day variability in physical activity and inactivity in 9- and 15-ye... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-21 |
Journal Detail:
|
Title: Pediatrics Volume: 125 ISSN: 1098-4275 ISO Abbreviation: Pediatrics Publication Date: 2010 Jan |
Date Detail:
|
Created Date: 2010-01-05 Completed Date: 2010-02-04 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0376422 Medline TA: Pediatrics Country: United States |
Other Details:
|
Languages: eng Pagination: e162-8 Citation Subset: AIM; IM |
Affiliation:
|
Department of Pediatrics, Montreal Children's Hospital, McGill University, Montreal, Quebec, Canada. evelyn.constantin@muhc.mcgill.ca |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Child Child, Preschool Confidence Intervals Cross-Sectional Studies False Negative Reactions Female Humans Logistic Models Male Odds Ratio Oximetry / methods* Polysomnography Probability Quality of Life* Quebec Questionnaires* Risk Assessment Sensitivity and Specificity Severity of Illness Index Sleep Apnea, Obstructive / diagnosis* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Improved care and growth outcomes by using hybrid humidified incubators in very preterm infants.
Next Document: Enzyme-replacement therapy in a 5-month-old boy with attenuated presymptomatic MPS I: 5-year follow-...