| Can "Inoperable" Congenital Heart Defects Become Operable in Patients with Pulmonary Arterial Hypertension? Dream or Reality? | |
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MedLine Citation:
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PMID: 22233186 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The decision whether to repair congenital heart defects in patients with raised pulmonary vascular resistance to alleviate pulmonary hypertension is a complex one. The degree of pulmonary vascular disease is of paramount importance. Operating on patients with pulmonary vascular resistance above a certain threshold runs the risk of postoperative persistent pulmonary hypertension and a worse long-term prognosis. This review focuses on patients deemed "borderline inoperable" or "inoperable" due to pulmonary vascular disease and asks whether they can be "converted to an operable status" with pulmonary arterial hypertension-specific drugs that potentially modify the pulmonary vascular lesions and resistance. |
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Authors:
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Maurice Beghetti; Nazzareno Galiè; Damien Bonnet |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-10 |
Journal Detail:
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Title: Congenital heart disease Volume: - ISSN: 1747-0803 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101256510 Medline TA: Congenit Heart Dis Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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© 2012 Wiley Periodicals, Inc. |
Affiliation:
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Pediatric Cardiology Unit, Department of the Child and Adolescent, Children's University Hospital, Geneva, Switzerland Institute of Cardiology, University of Bologna, Bologna, Italy French Reference Center for Complex Congenital Heart Diseases, Necker Hospital, University Paris Descartes, Paris, France. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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