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Can "Inoperable" Congenital Heart Defects Become Operable in Patients with Pulmonary Arterial Hypertension? Dream or Reality?
MedLine Citation:
PMID:  22233186     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
The decision whether to repair congenital heart defects in patients with raised pulmonary vascular resistance to alleviate pulmonary hypertension is a complex one. The degree of pulmonary vascular disease is of paramount importance. Operating on patients with pulmonary vascular resistance above a certain threshold runs the risk of postoperative persistent pulmonary hypertension and a worse long-term prognosis. This review focuses on patients deemed "borderline inoperable" or "inoperable" due to pulmonary vascular disease and asks whether they can be "converted to an operable status" with pulmonary arterial hypertension-specific drugs that potentially modify the pulmonary vascular lesions and resistance.
Authors:
Maurice Beghetti; Nazzareno Galiè; Damien Bonnet
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-1-10
Journal Detail:
Title:  Congenital heart disease     Volume:  -     ISSN:  1747-0803     ISO Abbreviation:  -     Publication Date:  2012 Jan 
Date Detail:
Created Date:  2012-1-11     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101256510     Medline TA:  Congenit Heart Dis     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 Wiley Periodicals, Inc.
Affiliation:
Pediatric Cardiology Unit, Department of the Child and Adolescent, Children's University Hospital, Geneva, Switzerland Institute of Cardiology, University of Bologna, Bologna, Italy French Reference Center for Complex Congenital Heart Diseases, Necker Hospital, University Paris Descartes, Paris, France.
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