Document Detail

Campylobacter peritonitis complicating peritoneal dialysis: a review of 12 consecutive cases.
MedLine Citation:
PMID:  23032087     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Peritoneal dialysis-associated peritonitis secondary to Campylobacter organisms is uncommon. Few studies have assessed either treatment or clinical outcomes.
METHODS: We reviewed all Campylobacter peritonitis episodes occurring in a single dialysis unit from 1994 to 2011.
RESULTS: During the study period, 12 episodes of Campylobacter peritonitis (0.45% of all peritonitis episodes) were recorded. Diarrhea was uncommon (8.3%). The overall primary response rate was 91.7%; the complete cure rate was 75.0%. Among 6 patients who failed to respond to standard antibiotics by day 5, all improved after administration of an oral macrolide (erythromycin or clarithromycin). Of those 6 patients, 5 experienced a complete cure, and 1 patient experienced relapse of culture-negative peritonitis. No patient required Tenckhoff catheter removal or temporary hemodialysis support. The 30-day mortality was 0%.
CONCLUSIONS: Campylobacter peritonitis might not respond to first-line conventional antibiotics, and an oral macrolide is recommended if Campylobacter is confirmed. The findings from our analysis do not support the use of fluoroquinolone, which is associated with a high resistance rate.
Terry King-wing Ma; Kin Ping Lee; Kai Ming Chow; Wing Fai Pang; Bonnie Ching Ha Kwan; Chi Bon Leung; Cheuk Chun Szeto; Philip Kam-tao Li
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2012-10-02
Journal Detail:
Title:  Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis     Volume:  33     ISSN:  1718-4304     ISO Abbreviation:  Perit Dial Int     Publication Date:    2013 Mar-Apr
Date Detail:
Created Date:  2013-03-12     Completed Date:  2013-09-26     Revised Date:  2014-03-09    
Medline Journal Info:
Nlm Unique ID:  8904033     Medline TA:  Perit Dial Int     Country:  Canada    
Other Details:
Languages:  eng     Pagination:  189-94     Citation Subset:  IM    
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MeSH Terms
Anti-Bacterial Agents / therapeutic use*
Campylobacter Infections / diagnosis,  drug therapy*,  etiology
Middle Aged
Peritoneal Dialysis / adverse effects*
Peritonitis / diagnosis,  drug therapy*,  etiology
Renal Insufficiency, Chronic / complications,  therapy*
Retrospective Studies
Treatment Outcome
Reg. No./Substance:
0/Anti-Bacterial Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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