| Campylobacter jejuni--microtubule-dependent invasion. | |
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MedLine Citation:
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PMID: 11514222 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Campylobacter jejuni is the leading bacterial cause of food-borne illness worldwide and a major cause of Guillain-Barré paralysis. Recent molecular and cellular studies of one well-characterized C. jejuni strain have begun to unravel the details of an unusual microtubule-dependent (actin-filament-independent) gut-invasion mechanism, through which at least some C. jejuni initiate disease. Although responsible for causing a human dysenteric syndrome remarkably similar to that triggered by Shigella spp., current evidence suggests that C. jejuni use some markedly different molecular mechanisms of pathogenesis compared with shigellae. |
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Authors:
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D J Kopecko; L Hu; K J Zaal |
Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Trends in microbiology Volume: 9 ISSN: 0966-842X ISO Abbreviation: Trends Microbiol. Publication Date: 2001 Aug |
Date Detail:
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Created Date: 2001-08-21 Completed Date: 2001-11-01 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9310916 Medline TA: Trends Microbiol Country: England |
Other Details:
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Languages: eng Pagination: 389-96 Citation Subset: IM |
Affiliation:
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Laboratory of Enteric and Sexually Transmitted Diseases, FDA-Center for Biologics Evaluation and Research, Bldg 29/420, NIH Campus, Bethesda, MD 20892, USA. kopecko@cber.fda.gov |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Campylobacter Infections
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microbiology* Campylobacter jejuni / genetics, pathogenicity* Dysentery, Bacillary / microbiology Epithelial Cells / microbiology Humans Intestines / cytology, microbiology Microtubules / microbiology*, physiology Virulence |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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