Document Detail

Campylobacter colitis in ranch mink in Ontario.
MedLine Citation:
PMID:  3742356     Owner:  NLM     Status:  MEDLINE    
Outbreaks of colitis, where Campylobacter jejuni and Campylobacter coli were the only pathogens isolated occurred in weanling mink (Mustella vision) on two commercial mink ranches in Ontario. Lesions were restricted to the proximal colon and were characterized by multiple 1 mm focal or 1 mm linear erosions/ulcers in the region 2 cm distal to the ileal-colonic junction. Histological changes included thickening of the colonic mucosa, inflammatory cell infiltrate in the lamina propria and submucosa, cellular debris and inflammatory exudate within cryptal lumens and multiple areas of mucosal erosion/ulceration. Four C. jejuni negative mink were challenged with 5.1 X 10(9) colony forming units of C. jejuni by oral inoculation. Three of four experimentally infected mink developed diarrhea by day 4 postinfection with lesions grossly and microscopically similar to mink in the naturally occurring outbreak. Examination of lesions by transmission electron microscope failed to show evidence of C. jejuni invasion of intestinal epithelium. Feeding uncooked slaughterhouse chicken offal was the likely source of C. jejuni in the naturally occurring outbreaks.
D B Hunter; J F Prescott; D M Hoover; G Hlywka; J A Kerr
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire     Volume:  50     ISSN:  0830-9000     ISO Abbreviation:  Can. J. Vet. Res.     Publication Date:  1986 Jan 
Date Detail:
Created Date:  1986-10-20     Completed Date:  1986-10-20     Revised Date:  2010-09-10    
Medline Journal Info:
Nlm Unique ID:  8607793     Medline TA:  Can J Vet Res     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  47-53     Citation Subset:  IM    
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MeSH Terms
Campylobacter Infections / epidemiology,  pathology,  veterinary*
Campylobacter fetus
Colitis, Ulcerative / epidemiology,  pathology,  veterinary*
Colon / pathology
Disease Outbreaks / epidemiology,  pathology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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