Document Detail


Camptocormia or Pisa syndrome in multiple system atrophy.
MedLine Citation:
PMID:  16112411     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Although a mild stooped posture is a hallmark of parkinsonism, extreme trunk forward flexion is not common. This phenomenon was described in different etiological entities and called camptocormia. Other similar presentations called Pisa syndrome and antecollis were described mainly in extrapyramidal disorders. Authors present two cases of probable multiple system atrophy (MSA) with predominant parkinsonism and Pisa syndrome (or camptocormia). Both of them were previously misdiagnosed as idiopathic Parkinson's disease (PD) and one was reported 1 year earlier. The typical clinical presentation fulfilling the diagnostic criteria for multiple system atrophy, rapid progression with lack of responsiveness to L-DOPA and apomorphine and typical MRI putaminal pathology observed in both cases allowed us to make a diagnosis. Accuracy of clinical diagnosis in multiple system atrophy is still very poor. Therefore, unusual or rare clinical presentations may support the final diagnosis. The camptocormia, Pisa syndrome and antecollis may represent the continuum of the same motor phenomenon and most of the authors refer them to unusual form of axial dystonia. According to many clinical presentations on different forms of camptocormia/Pisa syndrome authors conclude that not etiology, but the localization of specific lesion, probably within putamen is responsible for that form of dystonia. In cases of parkinsonism and severe forward flexion of trunk multiple system atrophy, diagnosis should be considered.
Authors:
Jarosław Sławek; Mirosława Derejko; Piotr Lass; Mirosława Dubaniewicz
Publication Detail:
Type:  Case Reports; Journal Article     Date:  2005-08-19
Journal Detail:
Title:  Clinical neurology and neurosurgery     Volume:  108     ISSN:  0303-8467     ISO Abbreviation:  Clin Neurol Neurosurg     Publication Date:  2006 Oct 
Date Detail:
Created Date:  2006-09-25     Completed Date:  2007-01-05     Revised Date:  2009-10-14    
Medline Journal Info:
Nlm Unique ID:  7502039     Medline TA:  Clin Neurol Neurosurg     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  699-704     Citation Subset:  IM    
Affiliation:
Department of Neurosurgery, Division of Functional Neurosurgery and Movement Disorders, Medical University, ul. Debinki 7, 80-211 Gdańsk, Poland. jaroslawek@amg.gda.pl
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MeSH Terms
Descriptor/Qualifier:
Diagnosis, Differential
Diagnostic Errors / prevention & control
Disease Progression
Dopamine Agonists / therapeutic use
Drug Resistance / physiology
Dystonic Disorders / diagnosis*,  etiology*,  physiopathology
Female
Humans
Magnetic Resonance Imaging
Middle Aged
Multiple System Atrophy / complications*,  diagnosis*,  physiopathology
Muscle, Skeletal / innervation,  physiopathology
Parkinson Disease / diagnosis,  drug therapy,  physiopathology
Putamen / pathology,  physiopathology
Spinal Curvatures / diagnosis*,  etiology*,  physiopathology
Spine / pathology,  physiopathology
Syndrome
Treatment Failure
Chemical
Reg. No./Substance:
0/Dopamine Agonists

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