| Camphor-derived C(1)-symmetric chiral diamine organocatalysts for asymmetric Michael addition of nitroalkanes to enones. | |
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MedLine Citation:
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PMID: 22893041 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A series of stable C(1)-symmetric chiral diamines () were conveniently synthesized by condensing exo-(-)-bornylamine or (+)-(1S,2S,5R)-menthylamine with various commercially available Cbz-protected amino acids. Among them, can efficiently promote the Michael addition of nitroalkanes to a broad scope of enones with high yields (up to 96%) and excellent enantioselectivities (up to 98%) under mild conditions. |
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Authors:
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Yirong Zhou; Qiang Liu; Yuefa Gong |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-8-14 |
Journal Detail:
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Title: Organic & biomolecular chemistry Volume: - ISSN: 1477-0539 ISO Abbreviation: Org. Biomol. Chem. Publication Date: 2012 Aug |
Date Detail:
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Created Date: 2012-8-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101154995 Medline TA: Org Biomol Chem Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, 1037 Luoyu Road, Wuhan 430074, People's Republic of China. gongyf@mail.hust.edu.cn. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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