| Calvarial defects associated with neurofibromatosis type 1. Report of two cases. | |
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MedLine Citation:
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PMID: 17566407 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Calvarial osteolysis is a relatively rare finding in patients with neurofibromatosis. The authors describe two patients with neurofibromatosis Type 1 (NF1) and extensive cranial defects associated with underlying dural ectasia. Cranioplasties were performed in both patients with mixed results. One patient underwent cranioplasty using titanium mesh and methylmethacrylate. The other patient underwent an extensive cranioplasty with autogenous iliac crest grafting, and after initial healing has since had further bone resorption. In conclusion, the results of cranial reconstruction in patients with NF1 and dural ectasia are unpredictable because of the tendency for further bone resorption; techniques that protect the graft material from cerebrospinal fluid pulsations via a rigid mesh should be considered. |
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Authors:
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John M K Mislow; Mark R Proctor; P Daniel McNeely; Arin K Greene; Gary F Rogers |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of neurosurgery Volume: 106 ISSN: 0022-3085 ISO Abbreviation: J. Neurosurg. Publication Date: 2007 Jun |
Date Detail:
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Created Date: 2007-06-14 Completed Date: 2007-06-27 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0253357 Medline TA: J Neurosurg Country: United States |
Other Details:
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Languages: eng Pagination: 484-9 Citation Subset: AIM; IM |
Affiliation:
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Department of Neurosurgery, Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA. jmislow@partners.org |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorbable Implants Adolescent Bone Plates Female Head / radiography Humans Ilium / transplantation Imaging, Three-Dimensional Male Neurofibromatosis 1 / complications* Neurosurgical Procedures* Osteolysis / etiology*, radiography, surgery* Skull* / radiography Surgical Mesh Titanium Tomography, X-Ray Computed |
| Chemical | |
Reg. No./Substance:
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7440-32-6/Titanium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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