| Calprotectin levels in oral fluids: the importance of collection site. | |
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MedLine Citation:
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PMID: 7600253 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Calprotectin is a major protein of granulocytes and monocytes with antimicrobial properties, and is released during activation or cell death. In the present study the levels of calprotectin in various oral fluids were analyzed in 12 healthy adults using different collection devices. Parotid saliva, stimulated whole saliva and "mucosal transudate" were collected and analyzed by enzyme-linked immunosorbent assay (ELISA). The results showed mean concentrations of 3.2, 22.0 and 40.9 mg/l in the respective oral fluids, illustrating great variation of calprotectin levels between different oral fluids. The results are in accordance with the composition of these saliva samples; the lowest calprotectin level was obtained in parotid saliva, which contains the purest secretion. These findings illustrate the importance of careful sampling procedures. The levels of salivary calprotectin are markedly influenced by the site of collection. |
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Authors:
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M Cuida; J G Brun; T Tynning; R Jonsson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European journal of oral sciences Volume: 103 ISSN: 0909-8836 ISO Abbreviation: Eur. J. Oral Sci. Publication Date: 1995 Feb |
Date Detail:
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Created Date: 1995-08-10 Completed Date: 1995-08-10 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 9504563 Medline TA: Eur J Oral Sci Country: DENMARK |
Other Details:
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Languages: eng Pagination: 8-10 Citation Subset: D; IM |
Affiliation:
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Broegelmann Research Laboratory for Microbiology, Department of Microbiology and Immunology, Gade Institute, University of Bergen, Norway. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Cell Adhesion Molecules, Neuronal / analysis* Enzyme-Linked Immunosorbent Assay Female Gingival Crevicular Fluid / chemistry*, immunology Humans Leukocyte L1 Antigen Complex Male Middle Aged Mouth Mucosa / chemistry, immunology Parotid Gland / secretion Reference Values Saliva / immunology Salivary Proteins and Peptides / analysis* Specimen Handling Tissue Distribution |
| Chemical | |
Reg. No./Substance:
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0/Cell Adhesion Molecules, Neuronal; 0/Leukocyte L1 Antigen Complex; 0/Salivary Proteins and Peptides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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