Document Detail


Calorie restriction and cellular proliferation in various tissues of the female Swiss Webster mouse.
MedLine Citation:
PMID:  2337899     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Two experiments have been conducted to determine the effects of calorie restriction on cellular proliferation in female mouse tissues. In the first experiment, 25% calorie restriction led to a decrease in cellular proliferation, measured by the [3H]thymidine labeling index, in each of the 7 tissues examined. The duct lining cells of the mammary gland were the most affected. This conclusion was confirmed in the second experiment in which levels of 0, 10, 20, 30 and 40% calorie restriction were employed. The difference in response of the duct cells of the mammary gland and the crypt cells of the colo-rectum is discussed in light of the opinion that the formation of cancer of these tissues in humans may be markedly affected by diet.
Authors:
E Lok; F W Scott; R Mongeau; E A Nera; S Malcolm; D B Clayson
Related Documents :
6299779 - Separation of vx-2 rabbit carcinoma-derived cells capable of releasing collagenase.
3165129 - Specific properties of epithelial and stromal cells from the endometrium of cows.
3496419 - Seeding of thymic microenvironments defined by distinct thymocyte-stromal cell interact...
19962139 - Heparin and low-molecular-weight heparins modulate the decidualization of human endomet...
12216959 - Potential uses of milk epithelial cells: a review.
9532009 - Paget's disease versus toker cell hyperplasia in a supernumerary nipple.
23758619 - Extracellular matrix domain formation as an indicator of chondrocyte dedifferentiation ...
2414369 - Keratin type intermediate filaments in sweat gland myoepithelial cells.
96269 - Cellular changes in the toad urinary bladder in response to metabolic acidosis.
Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Cancer letters     Volume:  51     ISSN:  0304-3835     ISO Abbreviation:  Cancer Lett.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-06-20     Completed Date:  1990-06-20     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7600053     Medline TA:  Cancer Lett     Country:  NETHERLANDS    
Other Details:
Languages:  eng     Pagination:  67-73     Citation Subset:  IM    
Affiliation:
Toxicology Research Division, Health and Welfare Canada, Banting Research Centre, Ottawa, Ontario.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Analysis of Variance
Animal Feed
Animal Nutritional Physiological Phenomena*
Animals
Body Weight
Cell Division*
Diet*
Esophagus / cytology
Female
Intestines / cytology
Mammary Glands, Animal / cytology
Mice
Mitotic Index
Skin / cytology
Urinary Bladder / cytology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Suppression of x-ray induced transformation by Valium and aspirin in mouse C3H10T1/2 cells.
Next Document:  Point mutations at codon 12 of C-K-ras in human endometrial carcinomas.