| Caloric sweetener consumption and dyslipidemia among US adults. | |
| | |
MedLine Citation:
|
PMID: 20407058 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
CONTEXT: Dietary carbohydrates have been associated with dyslipidemia, a lipid profile known to increase cardiovascular disease risk. Added sugars (caloric sweeteners used as ingredients in processed or prepared foods) are an increasing and potentially modifiable component in the US diet. No known studies have examined the association between the consumption of added sugars and lipid measures. OBJECTIVE: To assess the association between consumption of added sugars and blood lipid levels in US adults. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional study among US adults (n = 6113) from the National Health and Nutrition Examination Survey (NHANES) 1999-2006. Respondents were grouped by intake of added sugars using limits specified in dietary recommendations (< 5% [reference group], 5%-<10%, 10%-<17.5%, 17.5%-<25%, and > or = 25% of total calories). Linear regression was used to estimate adjusted mean lipid levels. Logistic regression was used to determine adjusted odds ratios of dyslipidemia. Interactions between added sugars and sex were evaluated. MAIN OUTCOME MEASURES: Adjusted mean high-density lipoprotein cholesterol (HDL-C), geometric mean triglycerides, and mean low-density lipoprotein cholesterol (LDL-C) levels and adjusted odds ratios of dyslipidemia, including low HDL-C levels (< 40 mg/dL for men; < 50 mg/dL for women), high triglyceride levels (> or = 150 mg/dL), high LDL-C levels (> or = 130 mg/dL), or high ratio of triglycerides to HDL-C (> 3.8). Results were weighted to be representative of the US population. RESULTS: A mean of 15.8% of consumed calories was from added sugars. Among participants consuming less than 5%, 5% to less than 17.5%, 17.5% to less than 25%, and 25% or greater of total energy as added sugars, adjusted mean HDL-C levels were, respectively, 58.7, 57.5, 53.7, 51.0, and 47.7 mg/dL (P < .001 for linear trend), geometric mean triglyceride levels were 105, 102, 111, 113, and 114 mg/dL (P < .001 for linear trend), and LDL-C levels modified by sex were 116, 115, 118, 121, and 123 mg/dL among women (P = .047 for linear trend). There were no significant trends in LDL-C levels among men. Among higher consumers (> or = 10% added sugars) the odds of low HDL-C levels were 50% to more than 300% greater compared with the reference group (< 5% added sugars). CONCLUSION: In this study, there was a statistically significant correlation between dietary added sugars and blood lipid levels among US adults. |
| | |
Authors:
|
Jean A Welsh; Andrea Sharma; Jerome L Abramson; Viola Vaccarino; Cathleen Gillespie; Miriam B Vos |
Related Documents
:
|
7025628 - Lipid measurements for coronary risk assessment: a review. 11570648 - The nature of the association between diet and serum lipids in the community: a twin st... 10376778 - Effect of pistachio nuts on serum lipid levels in patients with moderate hypercholester... 7604798 - Effects of fluvastatin and pravastatin on lipid profiles and thromboxane production in ... 22032358 - Animal performance and milk fatty acid profile of dairy goats fed diets with different ... 9537698 - A stable animal model of diet-induced calcium oxalate crystalluria. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: JAMA : the journal of the American Medical Association Volume: 303 ISSN: 1538-3598 ISO Abbreviation: JAMA Publication Date: 2010 Apr |
Date Detail:
|
Created Date: 2010-04-21 Completed Date: 2010-04-22 Revised Date: 2011-08-01 |
Medline Journal Info:
|
Nlm Unique ID: 7501160 Medline TA: JAMA Country: United States |
Other Details:
|
Languages: eng Pagination: 1490-7 Citation Subset: AIM; IM |
Affiliation:
|
Nutrition and Health Science Program, Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, GA, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Cross-Sectional Studies Dietary Sucrose* Dyslipidemias / epidemiology* Female Humans Male Middle Aged Nutrition Surveys United States / epidemiology |
| Grant Support | |
ID/Acronym/Agency:
|
K23 DK080953-02/DK/NIDDK NIH HHS; K23 DK080953-03/DK/NIDDK NIH HHS; K23 DK080953-04/DK/NIDDK NIH HHS; K23DK080953/DK/NIDDK NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Dietary Sucrose |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Early vs late tracheotomy for prevention of pneumonia in mechanically ventilated adult ICU patients:...
Next Document: Spoken language development in children following cochlear implantation.